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深入探究与癌症相关的挥发性有机化合物。

Digging deeper into volatile organic compounds associated with cancer.

作者信息

Janfaza Sajjad, Khorsand Babak, Nikkhah Maryam, Zahiri Javad

机构信息

School of Engineering, University of British Columbia, Kelowna, BC, Canada.

Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Jalal Ale Ahmad Highway, Tehran 14117, Iran.

出版信息

Biol Methods Protoc. 2019 Nov 27;4(1):bpz014. doi: 10.1093/biomethods/bpz014. eCollection 2019.

Abstract

Volatile organic compounds (VOCs), produced and emitted through the metabolism of cancer cells or the body's immune system, are considered novel cancer biomarkers for diagnostic purposes. Of late, a large number of work has been done to find a relationship between VOCs' signature of body and cancer. Cancer-related VOCs can be used to detect several types of cancers at the earlier stages which in turn provide a significantly higher chance of survival. Here we aim to provide an updated picture of cancer-related VOCs based on recent findings in this field focusing on cancer odor database.

摘要

挥发性有机化合物(VOCs)是通过癌细胞代谢或人体免疫系统产生并释放的,被认为是用于诊断目的的新型癌症生物标志物。近来,人们开展了大量工作来探寻VOCs的身体特征与癌症之间的关系。与癌症相关的VOCs可用于在早期阶段检测多种类型的癌症,进而显著提高患者的生存几率。在此,我们旨在基于该领域的最新研究成果,以癌症气味数据库为重点,提供一份关于与癌症相关的VOCs的最新情况概述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e31/6994028/a7f0178902bd/bpz014f1.jpg

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