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阿尔茨海默型老年痴呆中海马CA1锥体细胞基底树突的定量高尔基研究

A quantitative Golgi study of basal dendrites of hippocampal CA1 pyramidal cells in senile dementia of Alzheimer type.

作者信息

Yamada M, Wada Y, Tsukagoshi H, Otomo E, Hayakawa M

机构信息

Department of Neurology, Tokyo Medical and Dental University, Japan.

出版信息

J Neurol Neurosurg Psychiatry. 1988 Aug;51(8):1088-90. doi: 10.1136/jnnp.51.8.1088.

Abstract

Basal dendrites of hippocampal CA1 pyramidal cells in senile dementia of Alzheimer type (SDAT) were studied quantitatively by the Golgi impregnation method. The present data suggested that basal dendrites of the pyramidal cells were decreased in number in SDAT, and that the dendritic decrease was associated with a decrease in size of their cell bodies.

摘要

采用高尔基染色法对阿尔茨海默型老年痴呆(SDAT)患者海马CA1区锥体细胞的基底树突进行了定量研究。目前的数据表明,SDAT患者锥体细胞的基底树突数量减少,且树突减少与其细胞体大小减小有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab97/1033121/87ab14293f83/jnnpsyc00543-0073-a.jpg

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