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人类嗜T淋巴细胞病毒I型相关脊髓病中的多模态诱发电位

Multimodality evoked potentials in HTLV-I associated myelopathy.

作者信息

Kakigi R, Shibasaki H, Kuroda Y, Endo C, Oda K, Ikeda A, Hashimoto K

机构信息

Department of Internal Medicine, Saga Medical School, Japan.

出版信息

J Neurol Neurosurg Psychiatry. 1988 Aug;51(8):1094-6. doi: 10.1136/jnnp.51.8.1094.

Abstract

Multimodality evoked potentials (EPs) consisting of somatosensory EPs (SEPs), visual EPs (VEPs) and brainstem auditory EPs (BAEPs) were studied in 16 cases with HTLV-I associated myelopathy (HAM). Median nerve SEPs were normal in all cases. In posterior tibial nerve SEPs, the potential recorded at the 12th thoracic spinal process was normal in every case but cortical components were significantly prolonged in 10 cases, although five of these showed no sensory impairment. BAEPs were normal in every case whose hearing was intact, but VEPs were abnormal in two cases whose visual acuities were normal. The present results in HAM indicate predominant lesion in the thoracic cord, and might also suggest some subclinical lesion in the visual pathway.

摘要

对16例人类嗜T淋巴细胞病毒I型(HTLV-I)相关脊髓病(HAM)患者进行了包括体感诱发电位(SEPs)、视觉诱发电位(VEPs)和脑干听觉诱发电位(BAEPs)的多模态诱发电位(EPs)研究。所有病例的正中神经SEP均正常。在胫后神经SEP中,第12胸椎棘突处记录的电位在每个病例中均正常,但10例患者的皮质成分明显延长,尽管其中5例无感觉障碍。听力正常的每个病例的BAEP均正常,但视力正常的2例患者的VEP异常。HAM的目前结果表明胸段脊髓存在主要病变,也可能提示视觉通路存在一些亚临床病变。

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