Department of Urology, Amphia, Breda, The Netherlands.
Urology, University Medical Center Groningen (UMCG), Groningen, The Netherlands.
Scand J Urol. 2020 Apr;54(2):101-104. doi: 10.1080/21681805.2020.1738544. Epub 2020 Mar 12.
To compare prostate cancer detection rates between end-fire and side-fire ultrasound guided prostate biopsy techniques. A prospective randomized controlled trial was performed in patients who underwent prostate biopsy between 2009 and 2014. Patients were randomly assigned to the end-fire or side fire biopsy groups and underwent transrectal ultrasound guided prostate biopsy. The overall prostate cancer detection rate was compared between the two probe configurations. Trial was registered at Clinical Trials.gov with identifier: NCT00851292. A total of 730 patients were included and randomized, 371 patients underwent prostate biopsy with side-fire probe and 359 patients with the end-fire probe. Prostate cancer detection rates were 52.4% in the end fire group and 45.6% in the side fire group ( = .066). No significant difference was found in detection rate of prostate cancer between the end-fire and side-fire probe in transrectal ultrasound guided prostate biopsy, neither for detection rate of prostate cancer in the apex.
比较经直肠超声引导前列腺活检中针尾向和侧向激发探头的前列腺癌检出率。本前瞻性随机对照试验纳入 2009 年至 2014 年间行经直肠超声引导前列腺穿刺活检的患者。患者随机分配至针尾向激发和侧向激发组，行经直肠超声引导前列腺穿刺活检。比较两种探头配置的总前列腺癌检出率。本试验于 ClinicalTrials.gov 注册，注册号为：NCT00851292。共纳入 730 例患者并进行随机分组，其中 371 例患者采用侧向激发探头，359 例患者采用针尾向激发探头。针尾向激发组的前列腺癌检出率为 52.4%，侧向激发组为 45.6%（=0.066）。经直肠超声引导前列腺穿刺活检中，针尾向激发和侧向激发探头的前列腺癌检出率，包括尖部前列腺癌的检出率，均无显著差异。
