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Preliminary development and evaluation of a parenteral emulsion formulation of penclomedine (NSC-338720; 3,5-dichloro-2,4-dimethoxy-6-trichloromethylpyridine): a novel, practically water insoluble cytotoxic agent.

作者信息

Prankerd R J, Frank S G, Stella V J

出版信息

J Parenter Sci Technol. 1988 May-Jun;42(3):76-81.

PMID:3216265
Abstract
摘要

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引用本文的文献

1
Dose-limiting neurotoxicity in a phase I study of penclomedine (NSC 388720, CRC 88-04), a synthetic alpha-picoline derivative, administered intravenously.在一项I期研究中，静脉注射合成α-甲基吡啶衍生物喷氯米定（NSC 388720，CRC 88-04）时出现了剂量限制性神经毒性。
Br J Cancer. 1998 Mar;77(5):808-11. doi: 10.1038/bjc.1998.131.