Lane Jennifer C E, Rodrigues Jeremy N, Furniss Dominic, Burn Edward, Poulter Robert, Gardiner Matthew D
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Department of Plastic Surgery, Stoke Mandeville Hospital, Aylesbury, UK.
J Hand Surg Eur Vol. 2020 Jun;45(5):436-442. doi: 10.1177/1753193420909753. Epub 2020 Mar 12.
We used UK Hand Registry data to study two aspects of basal thumb osteoarthritis surgery: first, whether health-related quality of life improves after surgery. Second, whether results from trials comparing simple trapeziectomy and trapeziectomy with ligament reconstruction and tendon interposition are reproducible in routine clinical practice. Prospectively collected EQ5D index and Patient Evaluation Measure part 2 data were compared at baseline and at 3, 6, and 12 months postoperatively in 1456 patients (median age 67 years; 78% female). A mixed-effects regression model was also used to determine the postoperative trajectory of these variables. There was a significant improvement in the EQ5D index (median + 0.15; (interquartile range 0 to 0.40)) and Patient Evaluation Measure (-22; (-33 to -10)) by 1 year postoperatively and with no meaningful difference between the two techniques. This study demonstrates health state utility gains after basal thumb osteoarthritis surgery regardless of surgical techniques used. III.
第一，术后与健康相关的生活质量是否改善。第二，比较单纯大多角骨切除术以及大多角骨切除术联合韧带重建和肌腱嵌入术的试验结果在常规临床实践中是否可重复。前瞻性收集了1456例患者（中位年龄67岁；78%为女性）的EQ5D指数和患者评估量表第2部分的数据，并在基线、术后3个月、6个月和12个月进行比较。还使用混合效应回归模型来确定这些变量的术后变化轨迹。术后1年时，EQ5D指数（中位数+0.15；四分位间距0至0.40）和患者评估量表（-22；（-33至-10））有显著改善，且两种技术之间无显著差异。这项研究表明，无论采用何种手术技术，拇指基底节骨关节炎手术后健康状态效用均有提高。 三。
