Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Analyst. 2020 Apr 7;145(7):2515-2519. doi: 10.1039/d0an00299b. Epub 2020 Mar 12.
Binding protein scaffolds, such as rcSso7d, have been investigated for use in diagnostic tests; however, the functional performance of rcSso7d has not yet been studied in comparison to antibodies. Here, we assessed the analyte-binding capabilities of rcSso7d and antibodies on cellulose with samples in buffer and 100% human serum.
结合蛋白支架,如 rcSso7d,已被用于诊断测试;然而,rcSso7d 的功能性能尚未与抗体进行比较研究。在这里,我们评估了 rcSso7d 和抗体在缓冲液和 100%人血清中的样品在纤维素上的分析物结合能力。