Weedle P B, Poston J W, Parish P A
J R Coll Gen Pract. 1988 Apr;38(309):156-8.
Data relating to the use of hypnotic medicines from a descriptive epidemiological study of drug use in 55 residential homes for elderly people were analysed. Of the 1888 residents included in the study, 435 (23.0%) were receiving a total of 448 hypnotic medicines. There was preferential prescribing of short-acting benzodiazepines but long-acting benzodiazepines represented 31.7% of all hypnotic drugs prescribed. The median duration of treatment with temazepam was 0.8 years and with nitrazepam 2.5 years. The proportion of residents receiving hypnotic medicines in each home varied from 3.6% to 60.0% with a median of 24.1%. This study indicates a need for general practitioners to review their prescribing of hypnotic medicines for elderly people, paying particular attention to the duration of treatment.
对一项针对55家养老院药物使用情况的描述性流行病学研究中有关催眠药物使用的数据进行了分析。在纳入研究的1888名居民中，435人（23.0%）共接受了448种催眠药物治疗。存在优先开具短效苯二氮䓬类药物的情况，但长效苯二氮䓬类药物占所有开具的催眠药物的31.7%。替马西泮的中位治疗时长为0.8年，硝西泮为2.5年。每家养老院接受催眠药物治疗的居民比例从3.6%至60.0%不等，中位数为24.1%。这项研究表明，全科医生有必要审查他们为老年人开具催眠药物的处方，尤其要关注治疗时长。
