Cuvelier M, Lasek A, Ngendahayo P, Théate I, Sass U, Roquet-Gravy P-P, Bulinckx A
Service de dermatologie, grand hôpital de Charleroi, rue de Villers 1, 6280 Loverval, Belgique.
Service de dermatologie, hôpital Saint-Vincent-De-Paul, boulevard de Belfort, BP 387, 59000 Lille, France.
Ann Dermatol Venereol. 2020 May;147(5):361-365. doi: 10.1016/j.annder.2019.09.610. Epub 2020 Mar 9.
Apocrine hidrocystomas are benign cystic tumors that develop from apocrine gland proliferation. In most cases, they are translucent solitary lesions of the face, generally found in the periorbital region, on the scalp or on the neck. More rarely, apocrine hidrocystomas may be multiple and appear on the ears, trunk, shoulders and genital area. They generally appear in adulthood, with only a few pediatric cases being reported, of which three in the genital area, with a solitary case of multiple hidrocystomas of the scrotum, although no cases of spontaneous involution of hidrocystomas have previously been reported.
Two boys aged 4 and 6 months were seen in consultation for small sub-millimeter size, subcutaneous, black lesions on the scrotum that appeared in the weeks following birth. Histological examination of these lesions resulted in a diagnosis of apocrine hidrocystoma. The children were seen again a few weeks later and the skin lesions had totally disappeared. We report two cases of multiple apocrine hidrocystomas on the scrotum with spontaneous involution diagnosed in a 4- and a 6-month-old boy.
Apocrine hidrocystomas are rare benign adnexal tumors that develop from apocrine sweat glands. They are considered as cystic proliferations of the apocrine glands rather than simple retention cysts. The main differential diagnosis of the rare cases of multiple apocrine hidrocystomas are eccrine hidrocystomas. The treatment of such lesions is based on surgical excision if they are isolated, daily application of topical atropine 1%, or CO laser for multiple apocrine hidrocystomas.
顶泌汗腺囊瘤是由顶泌汗腺增生形成的良性囊性肿瘤。大多数情况下,它们是面部半透明的孤立性病变,通常见于眶周区域、头皮或颈部。更罕见的是,顶泌汗腺囊瘤可能为多发性,出现在耳部、躯干、肩部和生殖器区域。它们一般在成年期出现,仅有少数儿科病例报道,其中3例发生在生殖器区域,有1例为阴囊多发性囊瘤,不过此前尚无顶泌汗腺囊瘤自发消退的病例报道。
两名分别为4个月和6个月大的男童因出生后数周阴囊出现亚毫米大小的皮下黑色小病变前来就诊。对这些病变进行组织学检查后诊断为顶泌汗腺囊瘤。几周后再次检查这两名儿童时,皮肤病变已完全消失。我们报告两例4个月和6个月大男童阴囊多发性顶泌汗腺囊瘤自发消退的病例。
顶泌汗腺囊瘤是罕见的起源于顶泌汗腺的良性附属器肿瘤。它们被认为是顶泌汗腺的囊性增生而非单纯的潴留囊肿。罕见的多发性顶泌汗腺囊瘤的主要鉴别诊断是小汗腺囊瘤。此类病变的治疗方法是,如果病变孤立,可采用手术切除;对于多发性顶泌汗腺囊瘤,可每日外用1%阿托品或采用二氧化碳激光治疗。