Alfadley A, Al Aboud K, Tulba A, Mourad M M
Departments of Medicine and Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Int J Dermatol. 2001 Feb;40(2):125-9. doi: 10.1046/j.1365-4362.2001.01126.x.
Multiple eccrine hidrocystomas of the face are a rare facial dermatosis for which no recent large series of cases has been reported.
To describe the clinicopathologic features of five cases of multiple eccrine hidrocystoma and to emphasize their similar characteristics.
The clinical and histologic features of five women with multiple eccrine hidrocystomas of the face are described.
All cases were middle-aged women with numerous, asymptomatic, skin-colored to bluish, papulonodular skin lesions, ranging from 2 to 5 mm in diameter, and mainly centrifacial in distribution. Histopathologically, all cases showed unilocular cysts in the dermis lined by two layers of cuboidal cells. Staining for S-100 protein was negative in the cyst wall in all cases. One case was treated with topical 1% atropine for 3 weeks with no significant improvement. No systemic side-effects were observed during this treatment.
Multiple eccrine hidrocystomas are a rare condition which might be confused clinically and histopathologically with apocrine hidrocystomas. To date, no effective treatment has been reported.
面部多发性小汗腺汗囊肿是一种罕见的面部皮肤病，近期尚无大量病例报道。
描述5例多发性小汗腺汗囊肿的临床病理特征，并强调其相似特征。
描述了5例面部多发性小汗腺汗囊肿女性患者的临床和组织学特征。
所有病例均为中年女性，有众多无症状的皮肤色至蓝色丘疹结节性皮肤损害，直径2至5毫米，主要分布于面部中央。组织病理学上，所有病例均显示真皮内单房囊肿，内衬两层立方细胞。所有病例囊肿壁S-100蛋白染色均为阴性。1例患者外用1%阿托品治疗3周，无明显改善。治疗期间未观察到全身副作用。
多发性小汗腺汗囊肿是一种罕见疾病，在临床和组织病理学上可能与大汗腺汗囊肿混淆。迄今为止，尚未报道有效的治疗方法。
