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出生地和职业暴露与美国西班牙裔/拉丁裔人群慢性支气管炎的关联,2008-2011 年。

Association of birthplace and occupational exposures with chronic bronchitis in US Hispanics/Latinos, 2008-2011.

机构信息

Thoracic Medicine and Surgery, Temple University, Philadelphia, Pennsylvania, US.

Division of Sleep Medicine, Brigham and Women's Hospital, Boston, Massachusetts, US.

出版信息

Occup Environ Med. 2020 May;77(5):344-350. doi: 10.1136/oemed-2019-106081. Epub 2020 Mar 12.

Abstract

OBJECTIVES

In the US, chronic bronchitis (CB) is common and is associated with substantial morbidity and mortality. Data on CB in the Hispanic/Latino population-a large, diverse US minority-are scarce. We aimed to test whether the prevalence of CB varies across Hispanic/Latino heritages and to identify CB risk factors, including occupational exposures, in this population.

METHODS

We analysed data from the Hispanic Community Health Study/Study of Latinos, a US population-based probability sample of participants aged 18-74 years (n=16 415) including those with Mexican, Puerto Rican, Dominican, Cuban, Central American and South American heritages. Participants who had a completed respiratory questionnaire and valid spirometric data were included in the analysis (n=13 259). CB, place of birth, heritage, occupational exposures and other risk factors were based on standardised questionnaires. The prevalence of CB was estimated using survey logistic regression-conditional marginal analysis.

RESULTS

The estimated (mean (95% CI)) overall adjusted prevalence of CB was 12.1% (9.3 to 15.6), with a large variation across heritages. Dominican heritage had a fivefold higher prevalence than South American heritage. US-born participants had a higher adjusted prevalence than their non-US-born counterparts (16.8% (12.5 to 22.1) vs 11.0% (8.5 to 14.10); p=0.022). Compared with non-exposed participants, those exposed to cleaning or disinfecting solutions had a higher adjusted prevalence of CB (12.6% (9.1 to 17.1) vs 11.8% (9.2 to 15.1); p=0.024).

CONCLUSIONS

The prevalence of CB was higher among Dominicans than other Hispanic/Latino heritages. CB was more prevalent among US-born participants and those exposed to cleaning and disinfecting solutions.

摘要

目的

在美国,慢性支气管炎(CB)较为常见,与较高的发病率和死亡率相关。关于西班牙裔/拉丁裔人群中 CB 的数据(美国的一个大型多元化少数族裔群体)十分匮乏。我们旨在检验西班牙裔/拉丁裔不同群体间 CB 的流行率是否存在差异,并确定该人群中 CB 的危险因素,包括职业暴露。

方法

我们分析了美国基于人群的概率样本——西班牙裔健康研究/拉丁裔研究中,年龄在 18-74 岁之间的参与者(n=16415)的数据,包括具有墨西哥裔、波多黎各裔、多米尼加裔、古巴裔、中美洲裔和南美洲裔背景的参与者。纳入了完成呼吸问卷和有效肺量计数据的参与者(n=13259)进行分析。根据标准化问卷评估 CB、出生地、遗传背景、职业暴露和其他危险因素。使用调查逻辑回归-条件边际分析估计 CB 的流行率。

结果

总体上,调整后的 CB 估计患病率(平均(95%CI))为 12.1%(9.3-15.6),不同遗传背景间差异较大。与南美洲裔相比,多米尼加裔的患病率高 5 倍。与非美国出生的参与者相比,在美国出生的参与者调整后的患病率更高(16.8%(12.5-22.1)vs 11.0%(8.5-14.10);p=0.022)。与未暴露于职业暴露的参与者相比,暴露于清洁或消毒剂的参与者 CB 的调整后患病率更高(12.6%(9.1-17.1)vs 11.8%(9.2-15.1);p=0.024)。

结论

与其他西班牙裔/拉丁裔群体相比,多米尼加裔的 CB 患病率更高。在美国出生和暴露于清洁和消毒剂的参与者中,CB 的患病率更高。

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