兽医教学医院中猫和狗基于培养经验选择美罗培南的用药模式及比较（2011 - 2018年）
Prescribing patterns and comparison of culture empiric-based selection of meropenem in cats and dogs in a veterinary teaching hospital (2011-2018).
作者信息
Cousto Lillian M, Weese J Scott, Bateman Shane W
机构信息
Department of Clinical Studies (Cousto, Bateman), Department of Pathobiology (Weese), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.
出版信息
Can Vet J. 2020 Mar;61(3):274-280.
The utilization of meropenem in a small animal veterinary teaching hospital over a 7-year period was retrospectively analyzed, and culture (CBD) empiric-based decisions (EBD) were compared. Meropenem was infrequently prescribed at a rate of 0.50 prescriptions/1000 admissions in cats and 0.58/1000 in dogs. The most common condition for meropenem prescription in both cats and dogs was septic peritonitis (15/52, 28.8%). Overall 65.4% of meropenem prescriptions were initiated without, or prior to, culture results indicating a need for the drug. Based on retrospective analysis of culture and susceptibility results, only 2.9% of empirical meropenem selections were indicated, while the majority were not indicated (52.9%), or of questionable indication (44.2%).
回顾性分析了美罗培南在一家小动物兽医教学医院7年期间的使用情况，并比较了基于培养（CBD）的经验性决策（EBD）。美罗培南的处方频率较低，猫的处方率为0.50张/1000例入院病例，狗的处方率为0.58张/1000例入院病例。猫和狗使用美罗培南最常见的情况是感染性腹膜炎（15/52，28.8%）。总体而言，65.4%的美罗培南处方是在培养结果表明需要使用该药物之前或没有培养结果的情况下开始的。根据对培养和药敏结果的回顾性分析，只有2.9%的经验性美罗培南选择是有指征的，而大多数没有指征（52.9%）或指征存疑（44.2%）。
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