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腰椎管狭窄症后路手术后 90 天再手术和再入院的风险因素。

Risk factors for 90-day reoperation and readmission after lumbar surgery for lumbar spinal stenosis.

机构信息

1Department of Orthopedic Surgery.

2Center for Spine Health, and.

出版信息

J Neurosurg Spine. 2019 Apr 5;31(1):20-26. doi: 10.3171/2019.1.SPINE18878. Print 2019 Jul 1.

Abstract

OBJECTIVES

The objective of this study was to evaluate the incidence and risk factors for 90-day readmission and reoperation after elective surgery for lumbar spinal stenosis (LSS).

METHODS

The authors performed a retrospective consecutive cohort analysis of patients undergoing posterior lumbar decompression with or without fusion for LSS with claudication from January 2014 through December 2015.

RESULTS

Data were collected on 1592 consecutive patients. The mean age at surgery was 67.4 ± 10.1 years and 45% of patients were female. The 90-day reoperation rate was 4.7%, and 69.3% of the reoperations occurred within the first 30 days. The 90-day readmission rate was 7.2%. Multivariable analysis showed that postoperative development of a surgical site infection (SSI; odds ratio [OR] 14.09, 95% confidence interval [CI] 7.86–25.18), acute kidney injury (AKI; OR 6.76, 95% CI 2.39–19.57), and urinary tract infection (UTI; OR 3.96, 95% CI 2.43–6.37), as well as a history of congestive heart failure (CHF; OR 3.03, 95% CI 1.69–5.28), were significant risk factors for readmission within 90 days. Male sex (OR 0.60, 95% CI 0.38–0.92) was associated with decreased odds for readmission. With regards to reoperation, development of SSI (OR 25.06, 95% CI 13.54–46.51), sepsis (OR 7.63, 95% CI 1.52–40.59), UTI (OR 2.54, 95% CI 1.31–4.76), and increased length of stay (LOS; OR 1.25, 95% CI 1.17–1.33) were found to be significant risk factors. A subsequent analysis found that morbid obesity (OR 6.99), history of coronary artery disease (OR 2.263), increased duration of surgery (OR 1.004), and LOS (OR 1.07) were significant risk factors for developing an SSI.

CONCLUSIONS

Overall, this study found rates of 4.7% and 7.2% for reoperation and readmission, respectively, within 90 days: 30.7% of the reoperations and 44.7% of the readmissions occurred beyond the first 30 days. A diagnosis of SSI, AKI, UTI, and history of CHF were significant factors for readmission, while male sex was associated with decreased odds for readmission. A diagnosis of SSI, sepsis, UTI, and increased LOS were found to be significant predictors for reoperation. Understanding 90-day complication rates is imperative because there has been increased discussion and healthcare policy extending the global postoperative window to 90 days. Current literature supports a readmission rate of 3%–9% after spine surgery. However, this literature either is limited to a 30-day window or does not stratify between different types of spine surgeries.

ABBREVIATIONS

AKI = acute kidney injury; BPH = benign prostate hyperplasia; CAD = coronary artery disease; CHF = congestive heart failure; CI = confidence interval; CMS = Centers for Medicare and Medicaid Services; COPD = chronic obstructive pulmonary disease; DM = diabetes mellitus; EBL = estimated blood loss; LOS = length of stay; LSS = lumbar spinal stenosis; OR = odds ratio; POUR = postoperative urinary retention; SSI = surgical site infection; UTI = urinary tract infection.

摘要

目的

本研究旨在评估腰椎管狭窄症(LSS)择期手术患者 90 天内再入院和再手术的发生率及风险因素。

方法

作者对 2014 年 1 月至 2015 年 12 月接受后路腰椎减压伴或不伴腰椎管狭窄症伴间歇性跛行融合术的患者进行了回顾性连续队列分析。

结果

共收集了 1592 例连续患者的数据。手术时的平均年龄为 67.4±10.1 岁,45%的患者为女性。90 天内再手术率为 4.7%,69.3%的再手术发生在第 30 天内。90 天内再入院率为 7.2%。多变量分析显示,术后发生手术部位感染(SSI;优势比[OR]14.09,95%置信区间[CI]7.86-25.18)、急性肾损伤(AKI;OR 6.76,95%CI 2.39-19.57)和尿路感染(UTI;OR 3.96,95%CI 2.43-6.37),以及充血性心力衰竭(CHF;OR 3.03,95%CI 1.69-5.28)病史是 90 天内再入院的显著危险因素。男性(OR 0.60,95%CI 0.38-0.92)与再入院几率降低相关。至于再手术,发生 SSI(OR 25.06,95%CI 13.54-46.51)、脓毒症(OR 7.63,95%CI 1.52-40.59)、UTI(OR 2.54,95%CI 1.31-4.76)和延长住院时间(OR 1.25,95%CI 1.17-1.33)是再手术的显著危险因素。进一步分析发现,病态肥胖(OR 6.99)、冠心病史(OR 2.263)、手术持续时间延长(OR 1.004)和住院时间延长(OR 1.07)是发生 SSI 的显著危险因素。

结论

总的来说,本研究发现 90 天内再手术和再入院的发生率分别为 4.7%和 7.2%:30.7%的再手术和 44.7%的再入院发生在第 30 天以后。SSI、AKI、UTI 和 CHF 病史是再入院的显著因素,而男性则与再入院几率降低相关。SSI、脓毒症、UTI 和延长的 LOS 被发现是再手术的显著预测因素。了解 90 天并发症的发生率是至关重要的,因为人们对全球术后窗口延长至 90 天的讨论和医疗保健政策一直在增加。目前的文献支持脊柱手术后再入院率为 3%-9%。然而,这些文献要么限于 30 天的时间窗口,要么没有对不同类型的脊柱手术进行分层。

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