Department of Surgery, A. Perrino Hospital, Brindisi, Italy.
Department of Medical and Surgical Sciences, University of Catanzaro, Catanzaro, Italy.
J Invest Surg. 2021 Oct;34(10):1089-1103. doi: 10.1080/08941939.2020.1740360. Epub 2020 Mar 13.
Acute appendicitis (AA) is one of the most common causes of abdominal pain requiring surgical intervention. Approximately 20% of AA cases are characterized by complications such as gangrene, abscesses, perforation, or diffuse peritonitis, which increase patients' morbidity and mortality. Diagnosis of AA can be difficult, and evaluation of clinical signs, laboratory index and imaging should be part of the management of patients with suspicion of AA.
This consensus statement was written in relation to the most recent evidence for diagnosis and treatment of AA, performing a literature review on the most largely adopted scientific sources. The members of the SPIGC (Italian Polispecialistic Society of Young Surgeons) worked jointly to draft it. The recommendations were defined and graded based on the current levels of evidence and in accordance with the criteria adopted by the American College of Chest Physicians (CHEST) for the strength of the recommendations.
Fever and migratory pain tend to be present in patients with suspicion of AA. Laboratory and radiological examinations are commonly employed in the clinical practice, but today also scoring systems based on clinical signs and laboratory data have slowly been adopted for diagnostic purpose. The clinical presentation of AA in children, pregnant and elderly patients can be unusual, leading to more difficult and delayed diagnosis. Surgery is the best option in case of complicated AA, whereas it is not mandatory in case of uncomplicated AA. Laparoscopic surgical treatment is feasible and recommended. Postoperative antibiotic treatment is recommended only in patients with complicated AA.
急性阑尾炎(AA)是最常见的需要手术干预的腹痛原因之一。约 20%的 AA 病例伴有并发症,如坏疽、脓肿、穿孔或弥漫性腹膜炎,这增加了患者的发病率和死亡率。AA 的诊断可能具有挑战性,对临床症状、实验室指标和影像学的评估应作为怀疑 AA 患者管理的一部分。
本共识声明是根据最近关于 AA 的诊断和治疗的证据编写的,对最广泛采用的科学来源进行了文献回顾。SPIGC(意大利多专科青年外科医生协会)的成员共同起草了本声明。建议根据当前的证据水平和美国胸科医师学会(CHEST)采用的标准进行定义和分级,以确定建议的强度。
怀疑 AA 的患者通常会出现发热和转移性腹痛。实验室和影像学检查在临床实践中常用,但如今,基于临床症状和实验室数据的评分系统也逐渐被用于诊断目的。儿童、孕妇和老年患者的 AA 临床表现可能不典型,导致更困难和延迟的诊断。对于复杂的 AA,手术是最佳选择,而对于不复杂的 AA,手术则不是强制性的。腹腔镜手术治疗是可行的,也是推荐的。仅在复杂的 AA 患者中推荐术后抗生素治疗。