Department of Ophthalmology and Visual Sciences, McGill University, Montreal, Quebec.
Vitreous Retina Macula Specialists of Toronto, Toronto, Ontario, Canada.
Curr Opin Ophthalmol. 2020 May;31(3):199-206. doi: 10.1097/ICU.0000000000000653.
This article reviews emerging technologies in retinal imaging, including their scientific background, clinical implications and future directions.
Fluorescence lifetime imaging ophthalmoscopy is a technology that will reveal biochemical and metabolic changes of the retina at the cellular level. Optical coherence tomography is evolving exponentially toward higher resolution, faster speed, increased portability and more cost effective. Adaptive optics scanning laser ophthalmoscopy fluorescein angiography will provide unprecedented detail of the retinal vasculature down to the level of capillaries, enabling earlier and more sensitive detection of retinal vascular diseases.
Continued developments in retinal imaging focus on improved resolution, faster speed and noninvasiveness, while providing new information on the structure-function relationship of the retina inclusive of metabolic activity at the cellular level.
本文综述了视网膜成像领域的新兴技术,包括它们的科学背景、临床意义和未来方向。
荧光寿命成像检眼镜是一项能够在细胞水平上揭示视网膜生化和代谢变化的技术。光学相干断层扫描技术正朝着更高的分辨率、更快的速度、更高的便携性和更具成本效益的方向指数级发展。自适应光学扫描激光检眼镜荧光血管造影将以前所未有的细节显示视网膜血管系统,甚至可以达到毛细血管的水平,从而更早、更敏感地发现视网膜血管疾病。
视网膜成像的持续发展聚焦于提高分辨率、速度和非侵入性,同时提供关于视网膜结构-功能关系的新信息,包括细胞水平的代谢活动。