Division of Maternal Fetal Medicine, Women & Infants Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, Rhode Island.
Obstet Gynecol. 2020 Apr;135(4):949-952. doi: 10.1097/AOG.0000000000003743.
It has long been observed that neonates born between 39 and 40 gestational weeks have the best perinatal outcomes. What has not been known, until recently, is whether these ideal perinatal outcomes would be achieved in neonates whose delivery was brought on intentionally in this window by labor induction. Recent randomized trials and large observational cohorts have answered this question: labor induction, as compared with expectant management, lowers the rate of cesarean delivery (without increasing other adverse maternal outcomes) and improves perinatal outcomes. For those women still pregnant, delivery at 39 weeks of gestation would simultaneously lower the number of cesarean deliveries and reduce the number of stillbirths and neonatal deaths in the United States.
长期以来,人们一直观察到,妊娠 39 至 40 周之间出生的新生儿具有最佳的围产期结局。直到最近,人们还不知道,如果通过引产将分娩提前到这个时间窗内,这些理想的围产期结局是否能够实现。最近的随机试验和大型观察队列已经回答了这个问题:与期待管理相比,引产降低了剖宫产率(而没有增加其他不良母亲结局),并改善了围产期结局。对于那些仍在怀孕的女性,在美国,在 39 周时分娩将同时降低剖宫产率,并减少死胎和新生儿死亡的数量。