Tenjin H, Hirakawa K, Mizukawa N, Yano I, Ohta T, Uchibori M, Hino A
Department of Neurosurgery, Kyoto Prefectural University of Medicine, Japan.
Neurosurgery. 1988 Dec;23(6):705-9. doi: 10.1227/00006123-198812000-00003.
We used a temperature-controlled thermoelectrical method, induced hypotension, and CO2 inhalation to obtain cerebral blood flow (CBF) measurements during surgery for investigation of the state of brain vasoreactivity in subarachnoid hemorrhage patients. The study included 11 patients who underwent 12 operations for ruptured intracranial aneurysms. The CBF data were analyzed to investigate the neurological state, presence or nonpresence of vasospasm, timing of the operation, and outcome of each patient. Autoregulation disturbance, in terms of reaction to hypotension, was consistently seen in patients in poor neurological states, and this disturbance was correlated with poor outcome. This simple monitoring system, used during emergency operations for ruptured aneurysm, was useful in predicting outcome.
我们采用温度控制热电法、诱导性低血压和吸入二氧化碳的方法，在蛛网膜下腔出血患者的手术过程中获取脑血流量（CBF）测量值，以研究脑血管反应性状态。该研究纳入了11例因颅内动脉瘤破裂接受了12次手术的患者。对CBF数据进行分析，以研究每位患者的神经状态、是否存在血管痉挛、手术时机和预后。在神经状态较差的患者中，始终可以观察到在对低血压的反应方面存在自动调节障碍，并且这种障碍与不良预后相关。这种在动脉瘤破裂急诊手术期间使用的简单监测系统，有助于预测预后。
