Viale G L, Cossu M, Cella F, Balestrero M, Rossi A, Masoni D
Department of Neurosurgery, University of Genoa Medical School, Italy.
Acta Neurochir (Wien). 1994;131(1-2):1-5. doi: 10.1007/BF01401447.
Forty-three patients were operated on for ruptured intracranial aneurysms during a 12-month-period. Intraoperative evaluation of cortical blood flow by means of a thermal diffusion probe was performed in 23 out of the 41 patients who were operated on for aneurysms of the anterior circulation. The autoregulation index was determined at the time of raising the systemic blood pressure after clipping of the aneurysm(s). No statistically significant difference was found between the averages of the autoregulation indexes calculated in the subgroups of patients submitted respectively to early or delayed surgery. There was no correlation of both cortical blood flow and autoregulation with either age of the patients, or preoperative neurological grade. On the contrary, the autoregulation index showed a statistically significant correlation with outcome.
在12个月期间，43例患者因颅内动脉瘤破裂接受了手术。在接受前循环动脉瘤手术的41例患者中，有23例在术中通过热扩散探头对皮质血流进行了评估。在夹闭动脉瘤后升高全身血压时测定了自动调节指数。在分别接受早期或延迟手术的患者亚组中计算出的自动调节指数平均值之间未发现统计学上的显著差异。皮质血流和自动调节与患者年龄或术前神经学分级均无相关性。相反，自动调节指数与预后呈统计学上的显著相关性。
