Eisenberg H M, Turner J W, Teasdale G, Rowan J, Feinstein R, Grossman R G
J Neurosurg. 1979 May;50(5):595-602. doi: 10.3171/jns.1979.50.5.0595.
The electrical excitability of the cortex was monitored during craniotomy in 10 patients with ruptured aneurysms, to test their ability to tolerate hypotensive anesthesia. Excitability was assessed by measuring the direct cortical response, a response evoked and recorded from the surface of the brain. Previous animal experiments had shown that this response can be used as an index of cerebral blood flow. In the 10 patients the response progressively declined as the blood pressure was lowered and increased when the pressure was restored. Observation of the direct cortical response during aneurysm operations is a practical method for evaluating the electrophysiological responsiveness of the cortex during hypotension, and the authors suggest that decreases in the amplitude of the response are related to decreased in local cerebral blood flow.
在10例破裂动脉瘤患者开颅手术期间监测皮质的电兴奋性，以测试其耐受低血压麻醉的能力。通过测量直接皮质反应来评估兴奋性，直接皮质反应是从脑表面诱发并记录的反应。先前的动物实验表明，这种反应可用作脑血流量的指标。在这10例患者中，随着血压降低，反应逐渐减弱，而当血压恢复时反应增强。在动脉瘤手术期间观察直接皮质反应是评估低血压期间皮质电生理反应性的一种实用方法，作者认为反应幅度的降低与局部脑血流量的减少有关。
