United Hospital, St Paul, Minnesota, USA
Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
J Neurointerv Surg. 2020 Nov;12(11):1076-1079. doi: 10.1136/neurintsurg-2020-015844. Epub 2020 Mar 13.
Rates of intra-arterial revascularization treatments (IAT) for acute ischemic stroke (AIS) are increasing in the USA. Using a multi-state stroke registry, we studied the trend in IAT use among patients with AIS over a period spanning 11 years. We examined the impact of IAT rates on hospital procedure volumes and patient outcome after stroke.
We used data from the Paul Coverdell National Acute Stroke Program (PCNASP) and explored trends in IAT between 2008 and 2018. Patient outcomes were examined by rates of IAT procedures across hospitals. Specifically, outcomes were compared across low-volume (<15 IAT per year), medium-volume (15-30 IAT per year), and high-volume hospitals (>30 IAT per year). Favorable outcome was defined as discharge to home.
There were 612 958 patients admitted with AIS to 687 participating hospitals within the PCNASP during this study. Only 2.9% of patients (mean age 68.5 years, 49.3% women) received IAT. The percent of patients with AIS receiving IAT increased from 1% in 2008 to 5.3% in 2018 (p<0.001). The proportion of low-volume hospitals decreased over time (p<0.001), and the proportions of medium-volume (p=0.007) and high-volume hospitals (p<0.001) increased between 2008 and 2018. When compared with medium-volume hospitals, high-volume hospitals had a higher (p<0.0001) and low-volume hospitals had a lower (p<0.0001) percent of patients discharged to home.
High-volume hospitals were associated with a higher rate of favorable outcome. With the increased use of IAT among patients with AIS, the proportion of low-volume hospitals performing IAT significantly decreased.
在美国,急性缺血性脑卒中(AIS)患者的动脉血管内再通治疗(IAT)的比例正在增加。本研究使用多州脑卒中注册数据库,研究了 11 年间 AIS 患者 IAT 使用率的变化趋势。我们还评估了 IAT 率对脑卒中后医院手术量和患者预后的影响。
我们使用了来自保罗·科弗戴尔国家急性脑卒中项目(PCNASP)的数据,并探索了 2008 年至 2018 年间 IAT 的趋势。通过医院的 IAT 程序比例来检查患者的预后。具体来说,通过低容量(每年 IAT <15 例)、中容量(每年 IAT 15-30 例)和高容量(每年 IAT >30 例)医院间的 IAT 程序率来比较结果。出院回家定义为良好预后。
在这项研究中,PCNASP 中有 612958 名 AIS 患者被收入 687 家参与医院。仅有 2.9%的患者(平均年龄 68.5 岁,49.3%为女性)接受了 IAT。接受 IAT 的 AIS 患者比例从 2008 年的 1%增加到 2018 年的 5.3%(p<0.001)。低容量医院的比例随时间减少(p<0.001),中容量(p=0.007)和高容量医院(p<0.001)的比例在 2008 年至 2018 年间增加。与中容量医院相比,高容量医院出院回家的患者比例更高(p<0.0001),低容量医院的比例更低(p<0.0001)。
高容量医院与良好预后的比例更高相关。随着 AIS 患者 IAT 的应用增加,行 IAT 的低容量医院的比例显著下降。