Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
National Wildlife Health Center, Madison, WI, USA.
Methods Mol Biol. 2020;2123:195-209. doi: 10.1007/978-1-0716-0346-8_15.
Avian infection studies with influenza A are an important means of assessing host susceptibility, viral pathogenesis, host responses to infection, mechanisms of transmission, viral pathotype, and viral evolution. Complex systems and natural settings may also be explored with carefully designed infection studies. In this chapter, we explore the elements of infection studies, general guidelines for choosing a virus to use, host selection, and many aspects of study design.
禽类感染流感病毒的研究是评估宿主易感性、病毒发病机制、宿主感染反应、传播机制、病毒病原型和病毒进化的重要手段。精心设计的感染研究也可以用于探索复杂系统和自然环境。在本章中，我们探讨了感染研究的要素、选择使用病毒的一般准则、宿主选择以及研究设计的许多方面。
