Becker W, Steck T, Albert P, Börner W
Clinic and Policlinic of Nuclear Medicine, University of Würzburg, FRG.
Nuklearmedizin. 1988 Dec;27(6):252-7.
A prospective study was designed to evaluate the efficacy of radionuclide hysterosalpingoscintigraphy using 99mTc-labelled human serum albumin macroaggregates in 17 patients (34 tubes). In normal females the macroaggregates migrate spontaneously through the female reproductive tract following application into the posterior vaginal fornix. They can be seen in the uterine fornix 20 min p.i. (range: 5-90 min) and as free pelvic activity 120 min p.i. (range 40-180 min). Free pelvic activity could also be demonstrated by culdocentesis. In infertile patients with failure of tubal patency images after 180 min offered no additional information. For the routine diagnosis camera images 5, 60 and 180 min p.i. are recommended. Using 5-10 MBq 99mTc the radiation exposure to the ovaries is about 1/9th of the exposure from a normal radiologic hysterosalpingogram. The reported data show results comparable with those of hysterosalpingography (HSG) in females with patent or with nonpermeable tubes, but in cases of high-pressure by patency by HSG the results of scintigraphy are superior to those of HSG. Moreover, this method provides new insights into sperm motility under various physiological and pathological conditions.
一项前瞻性研究旨在评估使用99mTc标记的人血清白蛋白大聚合体进行放射性核素子宫输卵管闪烁造影术在17例患者（34条输卵管）中的疗效。在正常女性中，大聚合体在注入阴道后穹窿后会自发通过女性生殖道。注射后20分钟（范围：5 - 90分钟）可在子宫穹窿处看到它们，注射后120分钟（范围40 - 180分钟）可看到盆腔内有游离活性物质。通过后穹窿穿刺也可证实盆腔内有游离活性物质。对于输卵管通畅失败的不孕患者，180分钟后的图像未提供额外信息。对于常规诊断，建议分别在注射后5分钟、60分钟和180分钟采集相机图像。使用5 - 10 MBq的99mTc，卵巢所受的辐射剂量约为正常放射学子宫输卵管造影的1/9。报告的数据显示，在输卵管通畅或不通的女性中，闪烁造影术的结果与子宫输卵管造影术（HSG）相当，但在HSG显示输卵管通畅且压力较高的情况下，闪烁造影术的结果优于HSG。此外，该方法为各种生理和病理条件下的精子活力提供了新的见解。
