Department of Pathology, School of Basic Medical Science, Shanghai Medical College, Fudan University, Shanghai, China.
Department of Nephrology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ultrastruct Pathol. 2020 Mar 3;44(2):245-248. doi: 10.1080/01913123.2020.1739791. Epub 2020 Mar 14.
Podocyte infolding glomerulopathy (PIG) is a special type of glomerular disease that has been proposed in recent years and has attracted considerable attention. PIG is characterized by the formation of microspheres and microtubules in thickened glomerular basement membrane (GBM) on electron microscopy (EM), which is recognized as podocyte cytoplasmic infolding to the GBM. However, to date, only a few cases of PIG have been reported. Herein, we report a case of a 33-year-old female with PIG with undifferentiated connective tissue disease (UCTD) in China and review the literature.
足细胞内褶肾小球病 (PIG) 是近年来提出的一种特殊类型的肾小球疾病,引起了相当大的关注。PIG 的特征是在电子显微镜 (EM) 下观察到增厚的肾小球基底膜 (GBM) 中形成微球体和微管,这被认为是足细胞细胞质向 GBM 的内褶。然而,迄今为止,仅报道了少数几例 PIG 病例。在此,我们报告了一例中国 33 岁女性 PIG 合并未分化结缔组织病 (UCTD) 的病例,并复习文献。