Chang Mei-Ying, Zhang Yu, Li Ming-Xu, Xuan Fang
Department of Nephrology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing 100853, China.
World J Clin Cases. 2023 Jul 6;11(19):4684-4691. doi: 10.12998/wjcc.v11.i19.4684.
Podocyte infolding glomerulopathy (PIG) is a newly described and rare glomerular disease. To date, only approximately 40 cases have been reported globally.
A 26-year-old female patient presented to our hospital with a complaint of intermittent edema of both lower limbs over the past 2 years. The patient was diagnosed with PIG. She was prescribed corticosteroid therapy in other hospitals during the initial stage, to which she had responded poorly and had developed femoral head necrosis. Therefore, we administered immunosuppressants, renin-angiotensin system inhibitors, combined with traditional Chinese medicine. The patient was followed for 1 year, during which her clinical condition improved.
Integrated Chinese and Western medicine may be effective for PIG treatment, which requires active intervention to improve prognosis.
足细胞内褶性肾小球病（PIG）是一种新描述的罕见肾小球疾病。迄今为止，全球仅报道了约40例病例。
一名26岁女性患者因过去2年双下肢间歇性水肿前来我院就诊。该患者被诊断为PIG。初始阶段她在其他医院接受了糖皮质激素治疗，但反应不佳并发生了股骨头坏死。因此，我们给予免疫抑制剂、肾素-血管紧张素系统抑制剂，并结合中药治疗。对该患者进行了1年的随访，在此期间她的临床状况有所改善。
中西医结合治疗PIG可能有效，需要积极干预以改善预后。
