微血管血液动力学综述：血流分布和组织氧合的控制。
A Review on Microvascular Hemodynamics: The Control of Blood Flow Distribution and Tissue Oxygenation.
机构信息
Department of Bioengineering, University of California, 9500 Gilman Drive, La Jolla, CA 92093-0412, USA.
Department of Bioengineering, University of California, 9500 Gilman Drive, La Jolla, CA 92093-0412, USA.
出版信息
Crit Care Clin. 2020 Apr;36(2):293-305. doi: 10.1016/j.ccc.2019.12.011. Epub 2020 Feb 10.
Abstract
The microcirculation is a complex network of vessels ranging from as large as 100 μm to as small as 5 μm. This complex network is responsible for the regulation of oxygen to the surrounding tissues and ensures metabolite washout. With a more complete understanding of the microcirculation's physiologic and pathologic tendencies, engineers can create new solutions to combat blood pathologies and shock-related diseases. Over the last number of decades a grown interest in the microcirculation has resulted in the development of fundamental techniques to quantify the microvasculature flow and the release of oxygen to tissues.
摘要
微循环是一个复杂的血管网络，范围从 100μm 到 5μm 不等。这个复杂的网络负责调节周围组织的氧气供应，并确保代谢物的清除。通过更全面地了解微循环的生理和病理倾向，工程师们可以创造新的解决方案来对抗血液病理学和休克相关疾病。在过去的几十年中，人们对微循环的兴趣日益浓厚，这导致了基本技术的发展，以量化微血管的血流和氧气向组织的释放。
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