Facile preparation of carbon nanotube-based molecularly imprinted monolithic stirred unit.

A lab-made stirring extraction unit based on a selective monolithic solid was developed. The monolith was formed by interconnected carbon nanotubes which were covered by a thin polymeric layer, where specific cavities were generated to provide selective recognition sites in the material. To reach this goal, a water-in-oil (W/O) medium internal phase emulsion (40/60 w/w%), was prepared and photopolymerized. The polymerization reaction took place in the organic or external phase containing the carbon nanotubes, polymeric monomers (cross-linker and functional monomer) and a molecule template. Therefore, it was possible to coat the nanotubes with a layer of molecularly imprinted polymer (MIP) with the target analyte while forming a monolithic and macroscopic structure. The developed selective monolithic stirring extraction units were applied for the determination of secbumeton and structurally related compounds (triazine herbicides) in peppermint mint and tea samples. Their adsorption capacity and selectivity were also compared with a non-imprinted polymer (NIP). Finally, the performance of the method was evaluated for quantitative analysis, achieving limits of detection (LODs) between 0.4 and 2.5 μg·L. The intra- and inter-day precision of the method was also evaluated as relative standard deviation, observing values which ranged from 3% to 9% and 9% to 15%, respectively. Graphical Abstract.