Independent Researcher, 28007 Madrid, Spain.
Chemical Optosensors and Applied Photochemistry Group (GSOLFA), Department of Analytical Chemistry, Facultad de Química, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Int J Mol Sci. 2023 Jan 18;24(3):1915. doi: 10.3390/ijms24031915.
Over the last decades, an increasing demand for new specific molecular recognition elements has emerged in order to improve analytical methods that have already been developed in order to reach the detection/quantification limits of target molecules. Molecularly imprinted polymers (MIPs) have molecular recognition abilities provided by the presence of a template molecule during their synthesis, and they are excellent materials with high selectivity for sample preparation. These synthetic polymers are relatively easy to prepare, and they can also be an excellent choice in the substitution of antibodies or enzymes in different kinds of assays. They have been properly applied to the development of chromatographic or solid-phase extraction methods and have also been successfully applied as electrochemical, piezoelectrical, and optical sensors, as well as in the catalysis process. Nevertheless, new formats of polymerization can also provide new applications for these materials. This paper provides a comprehensive comparison of the new challenges in molecular imprinting as materials of the future in Spain.
在过去的几十年中，为了提高已经开发出的分析方法以达到目标分子的检测/定量极限，对新型特定分子识别元件的需求不断增加。分子印迹聚合物（MIPs）在其合成过程中存在模板分子，从而具有分子识别能力，并且是用于样品制备的具有高选择性的出色材料。这些合成聚合物易于制备，并且在不同类型的测定中替代抗体或酶也是一个极好的选择。它们已被适当应用于色谱或固相萃取方法的开发，并且还成功地应用于电化学，压电和光学传感器，以及催化过程中。不过，聚合的新形式也可以为这些材料提供新的应用。本文全面比较了西班牙未来分子印迹材料的新挑战。
