Hamdy Doaa Ahmed, Abd El Wahab Wegdan Mohamed, Senosy Shaimaa Ahmed, Mabrouk Amna Gouda
1Department of Medical Parasitology, College of Medicine, Beni-Suef University, Beni-Suef, Egypt.
2Department of Public Health and Community Medicine, College of Medicine, Beni-Suef University, Beni-Suef, Egypt.
J Parasit Dis. 2020 Mar;44(1):88-98. doi: 10.1007/s12639-019-01165-9. Epub 2019 Oct 8.
and spp. are two common zoonotic intestinal parasites responsible for the majority of diarrheic cases, especially in children. The study was planned to determine the impact role of both and co-infection in children up to 12 years old with acute diarrhea in Beni-Suef, Egypt. Also, to estimate the general prevalence rates and risk factors associated with intestinal parasitic infections. Stool samples collected from 125 children, within a period of 7 months, were examined using direct wet mount and trichrome stain in comparison to in vitro culture on Jones medium (for detecting spp.) and Immunochromatography techniques (for detecting ). At least one type of intestinal parasites was harbored in 72% of the studied children, single infection constituted 37.6% while, 34.4% were polyparasitized children. The predominant parasites involved were spp.(53.6%), followed by (27.2%). Co-infection between both parasites was recorded in 20% of cases. Two risk factors were significantly associated with higher risk of - co-infection including age category (5-7 years) and family size (≥ 6 members) by univariate analysis ( = 0.004, 0.009 respectively) and also by the multivariate model (OR = 0.526, 0.336). Abdominal pain was the only gastrointestinal manifestation associated with the co-infection using the univariate analysis ( = 0.0427). The present study detects a high prevalence of intestinal parasitic infection; in particular, - co-infection in diarrheic young children (up to 12 years) in Beni-Suef Governorate, Egypt and recommends further subtypes identification of both parasites.
[寄生虫名称1]和[寄生虫名称2]是两种常见的人畜共患肠道寄生虫,是导致大多数腹泻病例的原因,尤其是在儿童中。本研究旨在确定[寄生虫名称1]和[寄生虫名称2]共同感染对埃及贝尼苏韦夫12岁以下急性腹泻儿童的影响作用。此外,还旨在估计肠道寄生虫感染的总体患病率以及相关危险因素。在7个月的时间内,从125名儿童中采集粪便样本,采用直接湿涂片法和三色染色法进行检测,并与琼斯培养基上的体外培养法(用于检测[寄生虫名称1])和免疫层析技术(用于检测[寄生虫名称2])进行比较。在72%的研究儿童中至少携带一种肠道寄生虫,单一感染占37.6%,而34.4%为多重寄生虫感染儿童。主要涉及的寄生虫是[寄生虫名称1](53.6%),其次是[寄生虫名称2](27.2%)。两种寄生虫的共同感染记录在20%的病例中。单因素分析显示,两个危险因素与[寄生虫名称1]和[寄生虫名称2]共同感染的较高风险显著相关,包括年龄组(5 - 7岁)和家庭规模(≥6名成员)(分别为P = 0.004,0.009),多变量模型分析结果也显示相关(OR = 0.526,0.336)。单因素分析显示,腹痛是与共同感染相关的唯一胃肠道表现(P = 0.0427)。本研究检测到肠道寄生虫感染的高患病率;特别是在埃及贝尼苏韦夫省腹泻幼儿(12岁以下)中[寄生虫名称1]和[寄生虫名称2]的共同感染,并建议对这两种寄生虫进行进一步的亚型鉴定。