• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

沙特阿拉伯儿童春季角结膜炎的管理

Management of vernal keratoconjunctivitis in children in Saudi Arabia.

作者信息

AlHarkan Dora Hamad

机构信息

Department of Ophthalmology, Medical College, Qassim University, Qassim, Saudi Arabia.

出版信息

Oman J Ophthalmol. 2020 Feb 17;13(1):3-12. doi: 10.4103/ojo.OJO_263_2018. eCollection 2020 Jan-Apr.

DOI:10.4103/ojo.OJO_263_2018
PMID:32174733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7050462/
Abstract

Vernal keratoconjunctivitis is a chronic inflammatory disease of the ocular surface and one of the worst types of allergic conjunctival diseases. Because of its chronic nature, it can damage the cornea, resulting in sight-threatening complications if left untreated. The disease affects mainly young children starting around the age of 7 years. We used keywords to search for published English articles in PUBMED, Google Scholar, EMBASE, and Cochrane Database of Systematic Reviews. Most of the published literature is focusing on general management of the disease and few publications focusing on treatment in the pediatric age group. We highlight the importance of how is the topical management differs between age groups. We focused on the importance of doing cycloplegic refraction for each child as the risk of keratoconus and oblique astigmatism is high in these cases. Furthermore, we highlight the importance of using eye lubricants as a therapeutic and preventive tool for the attacks of the disease. We highlight that most of the recent effective medications (especially the off-label ones) are not available in Saudi Arabia, such as tacrolimus, and some are only available to be prepared in tertiary center pharmacies as Cyclosporine A with higher concentrations.

摘要

春季角结膜炎是一种眼表慢性炎症性疾病,也是最严重的变应性结膜疾病之一。因其具有慢性特点,如果不治疗,它会损害角膜,导致威胁视力的并发症。该疾病主要影响7岁左右开始发病的儿童。我们使用关键词在PubMed、谷歌学术、EMBASE和Cochrane系统评价数据库中搜索已发表的英文文章。大多数已发表的文献聚焦于该疾病的一般管理,而很少有文献关注儿科年龄组的治疗。我们强调了不同年龄组局部治疗差异的重要性。我们关注到对每个儿童进行睫状肌麻痹验光的重要性,因为这些病例中圆锥角膜和斜散光的风险很高。此外,我们强调了使用眼部润滑剂作为该疾病发作的治疗和预防工具的重要性。我们强调最近的大多数有效药物(尤其是未按药品说明书用药的药物)在沙特阿拉伯无法获得,如他克莫司,有些药物仅在三级中心药房才能配制高浓度的环孢素A。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef0/7050462/89d3d1d3a0ce/OJO-13-3-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef0/7050462/d84bca04baf3/OJO-13-3-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef0/7050462/89d3d1d3a0ce/OJO-13-3-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef0/7050462/d84bca04baf3/OJO-13-3-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ef0/7050462/89d3d1d3a0ce/OJO-13-3-g002.jpg

相似文献

1
Management of vernal keratoconjunctivitis in children in Saudi Arabia.沙特阿拉伯儿童春季角结膜炎的管理
Oman J Ophthalmol. 2020 Feb 17;13(1):3-12. doi: 10.4103/ojo.OJO_263_2018. eCollection 2020 Jan-Apr.
2
Vernal keratoconjunctivitis: a severe allergic eye disease with remodeling changes.春季角结膜炎:一种伴有重塑改变的严重过敏性眼部疾病。
Pediatr Allergy Immunol. 2014 Jun;25(4):314-22. doi: 10.1111/pai.12197. Epub 2014 Jan 20.
3
Vernal Keratoconjunctivitis.春季角结膜炎。
Surv Ophthalmol. 2019 May-Jun;64(3):289-311. doi: 10.1016/j.survophthal.2018.12.001. Epub 2018 Dec 12.
4
Tear cytokines in acute and chronic ocular allergic inflammation.急性和慢性眼部过敏性炎症中的泪液细胞因子
Curr Opin Allergy Clin Immunol. 2004 Oct;4(5):441-5. doi: 10.1097/00130832-200410000-00018.
5
Therapeutic effects of topical 0.03% Tacrolimus ointment in children with refractory vernal keratoconjunctivitis in Middle East.0.03%他克莫司软膏局部治疗中东地区儿童难治性春季角结膜炎的疗效
Saudi J Ophthalmol. 2019 Apr-Jun;33(2):117-120. doi: 10.1016/j.sjopt.2019.04.001. Epub 2019 May 17.
6
Tacrolimus vs. cyclosporine eyedrops in severe cyclosporine-resistant vernal keratoconjunctivitis: A randomized, comparative, double-blind, crossover study.他克莫司与环孢素滴眼液治疗重度环孢素抵抗性春季角结膜炎的随机、对照、双盲、交叉研究
Pediatr Allergy Immunol. 2015 May;26(3):256-261. doi: 10.1111/pai.12360.
7
Allergic chronic inflammation of the ocular surface in vernal keratoconjunctivitis.春季角结膜炎中眼表的过敏性慢性炎症。
Curr Opin Allergy Clin Immunol. 2003 Oct;3(5):381-7. doi: 10.1097/00130832-200310000-00011.
8
Long-term safety and efficacy of topical cyclosporine in 156 children with vernal keratoconjunctivitis.环孢素滴眼液治疗儿童春季角结膜炎 156 例的长期安全性和疗效。
Int J Immunopathol Pharmacol. 2010 Jul-Sep;23(3):865-71. doi: 10.1177/039463201002300322.
9
Corneal complications of vernal keratoconjunctivitis.春季角结膜炎的角膜并发症
Curr Opin Allergy Clin Immunol. 2015 Oct;15(5):489-94. doi: 10.1097/ACI.0000000000000202.
10
Vernal Keratoconjunctivitis in Kashmir: A temperate zone.克什米尔地区的春季角结膜炎:一个温带地区。
Int Ophthalmol. 2016 Dec;36(6):875-879. doi: 10.1007/s10792-016-0213-8. Epub 2016 Mar 10.

引用本文的文献

1
Clinical characteristics of allergic conjunctivitis in the Southern region of Saudi Arabia: a cross-sectional study.沙特阿拉伯南部地区过敏性结膜炎的临床特征:一项横断面研究。
Ther Adv Ophthalmol. 2024 Nov 4;16:25158414241294020. doi: 10.1177/25158414241294020. eCollection 2024 Jan-Dec.
2
Parents' Knowledge and Attitudes Toward Pediatric Ophthalmic Disorders in Saudi Arabia: A Cross-Sectional Study.沙特阿拉伯父母对小儿眼科疾病的认知与态度:一项横断面研究
Pediatr Rep. 2024 Oct 17;16(4):902-920. doi: 10.3390/pediatric16040077.
3
Vernal Keratoconjunctivitis: A Systematic Review.

本文引用的文献

1
Vernal keratoconjunctivitis.春季角结膜炎
Clin Ophthalmol. 2018 Jan 11;12:119-123. doi: 10.2147/OPTH.S129552. eCollection 2018.
2
Clinical implications of mast cell involvement in allergic conjunctivitis.肥大细胞参与变应性结膜炎的临床意义。
Allergy. 2018 Mar;73(3):528-539. doi: 10.1111/all.13334. Epub 2017 Nov 20.
3
Japanese guidelines for allergic conjunctival diseases 2017.《2017年日本过敏性结膜疾病诊疗指南》
春季角结膜炎:系统评价。
Clin Rev Allergy Immunol. 2023 Aug;65(2):277-329. doi: 10.1007/s12016-023-08970-4. Epub 2023 Sep 2.
4
Diagnosis, Management, and Treatment of Vernal Keratoconjunctivitis in Asia: Recommendations From the Management of Vernal Keratoconjunctivitis in Asia Expert Working Group.亚洲春季角结膜炎的诊断、管理与治疗:亚洲春季角结膜炎管理专家工作组的建议
Front Med (Lausanne). 2022 Aug 1;9:882240. doi: 10.3389/fmed.2022.882240. eCollection 2022.
5
Multivariate analysis of the effect of Chalazia on astigmatism in children.多变量分析霰粒肿对儿童散光的影响。
BMC Ophthalmol. 2022 Jul 17;22(1):310. doi: 10.1186/s12886-022-02529-1.
6
Giant Papilla Prolapse from the Upper Tarsal Conjunctiva in a 3-year-old Child: A Case Presentation and a Brief Literature Review.一名3岁儿童上睑结膜巨大乳头脱垂:病例报告及文献综述
Beyoglu Eye J. 2021 Feb 10;6(1):70-73. doi: 10.14744/bej.2021.65807. eCollection 2021.
Allergol Int. 2017 Apr;66(2):220-229. doi: 10.1016/j.alit.2016.12.004. Epub 2017 Feb 10.
4
Diagnosis and management of allergic conjunctivitis in pediatric patients.儿童过敏性结膜炎的诊断与管理
Allergy Asthma Proc. 2017 Jan 1;38(1):16-27. doi: 10.2500/aap.2017.38.4003.
5
Prevalence and associated factors of vernal keratoconjunctivitis among children in Gondar city, Northwest Ethiopia.埃塞俄比亚西北部贡德尔市儿童春季角结膜炎的患病率及相关因素
BMC Ophthalmol. 2016 Sep 29;16(1):167. doi: 10.1186/s12886-016-0345-7.
6
Common Eye Diseases in Children in Saudi Arabia (Jazan).沙特阿拉伯(吉赞)儿童常见眼病
Ophthalmol Eye Dis. 2016 Sep 20;8:33-9. doi: 10.4137/OED.S39055. eCollection 2016.
7
An Update on the Therapeutic Approach to Vernal Keratoconjunctivitis.春季角结膜炎治疗方法的最新进展
Paediatr Drugs. 2016 Oct;18(5):347-55. doi: 10.1007/s40272-016-0185-1.
8
Topical Olopatadine in the Treatment of Allergic Conjunctivitis: A Systematic Review and Meta-analysis.标题:奥洛他定治疗过敏性结膜炎的系统评价和荟萃分析。
Ocul Immunol Inflamm. 2017 Oct;25(5):663-677. doi: 10.3109/09273948.2016.1158282. Epub 2016 May 18.
9
Impact of Vernal Keratoconjunctivitis on School Children in Egypt.春季角结膜炎对埃及学龄儿童的影响
Semin Ophthalmol. 2017;32(5):543-549. doi: 10.3109/08820538.2015.1123737. Epub 2016 Apr 29.
10
Effect of Allergic Diseases on Keratoconus Severity.变应性疾病对角圆锥角膜严重程度的影响。
Ocul Immunol Inflamm. 2017 Jun;25(3):418-423. doi: 10.3109/09273948.2016.1145697. Epub 2016 Mar 25.