Department of Ophthalmology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders. China International Science and Technology Cooperation base of Child Development and Critical Disorders. Chongqing Key Laboratory of Pediatrics, 136 zhongshan 2nd RD, Yuzhong District, Chongqing, 400014, China.
BMC Ophthalmol. 2022 Jul 17;22(1):310. doi: 10.1186/s12886-022-02529-1.
Chalazion may affect visual acuity. This study aimed to evaluate refractive status of chalazia and effect of different sites, sizes, and numbers of chalazion on astigmatism.
Three hundred ninety-eight patients aged 0.5-6 years were divided into the chalazion group (491 eyes) and the control group (305 eyes). Chalazia were classified according to the site, size, and number. Refractive status was analyzed through the comparison of incidence, type, mean value and vector analysis.
The incidence, type, refractive mean and of astigmatism in the chalazion group were higher than those in the control group, and the difference was statistically significant (P < 0.05). For comparison of the incidence, the middle-upper eyelid (50%) was highest, followed by 41.77% in the medial-upper eyelid, both higher than that in the control group (P < 0.05). In medium (54.55%) and large groups (54.76%) were higher than that in the control group (27.21%) (P < 0.05). In multiple chalazia, the astigmatism incidence for chalazion with two masses was highest (56%), much higher than that in the control group (P < 0.05). However, this difference was not significant in chalazion with ≥3 masses (P > 0.05). For comparison of the refractive mean,the medial-upper eyelid, middle-upper eyelid and medial-lower eyelid were higher than the control group (P < 0.05) (P < 0.05). The 3-5 mm and >5 mm group were higher than those in the control group and <3 mm group(P < 0.05), and the>5 mm group was larger than the 3-5 mm group，suggesting that the risk of astigmatism was higher when the size of masses > 5 mm. Astigmatism vector analysis can intuitively show the differences between groups, the results are the same as refractive astigmatism.
Chalazia in children can easily lead to astigmatism, especially AR and OBL. Chalazia in the middle-upper eyelid, size ≥3 mm, and multiple chalazia (especially two masses) are risk factors of astigmatism. Invasive treatment should be performed promptly if conservative treatment cannot avoid further harm to the visual acuity due to astigmatism.
霰粒肿可能会影响视力。本研究旨在评估霰粒肿的屈光状态，以及不同部位、大小和数量的霰粒肿对散光的影响。
将 398 例 0.5-6 岁患儿分为霰粒肿组（491 眼）和对照组（305 眼）。根据部位、大小和数量对霰粒肿进行分类。通过比较发生率、类型、平均值和向量分析来分析屈光状态。
霰粒肿组的发生率、类型、平均屈光值和散光值均高于对照组，差异有统计学意义（P<0.05）。在发生率比较中，中上部睑（50%）最高，其次是内上睑（41.77%），均高于对照组（P<0.05）。中大型（54.55%和 54.76%）高于对照组（27.21%）（P<0.05）。多发性霰粒肿中，两个肿块的霰粒肿发生率最高（56%），明显高于对照组（P<0.05）。但是，两个以上肿块的霰粒肿发生率差异无统计学意义（P>0.05）。在平均屈光值比较中，内上睑、中上部睑和内下睑高于对照组（P<0.05）（P<0.05）。3-5mm 和>5mm 组高于对照组和<3mm 组（P<0.05），>5mm 组大于 3-5mm 组，提示肿块大小>5mm 时，散光风险较高。散光向量分析可直观显示组间差异，结果与屈光性散光一致。
儿童霰粒肿易导致散光，尤其是远视散光和斜轴散光。中上部睑、≥3mm 大小和多发性霰粒肿（尤其是两个肿块）是散光的危险因素。如果保守治疗不能避免因散光而进一步损害视力，应及时进行有创治疗。
