Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
Center for Assisted Reproduction, Krishna IVF Clinic, Visakhapatnam, India.
Front Endocrinol (Lausanne). 2020 Feb 27;11:105. doi: 10.3389/fendo.2020.00105. eCollection 2020.
Although individualization of ovarian stimulation aims at maximal efficacy and safety in assisted reproductive treatments, in its current form it is far from ideal in achieving the desired success in women with a low prognosis. This could be due a failure to identify such women who are likely to have a low prognosis with currently used prognostic characteristics. Introduction of the patient-oriented strategies encompassing individualized oocyte number (POSEIDON) concept reinforces recognizing such low prognosis groups and stratifying in accordance with important prognostic factors. The POSEIDON concept provides a practical approach to the management of these women and is a useful tool for both counseling and clinical management. In this commentary, we focus on likely management strategies for POSEIDON group 2 criteria.
虽然卵巢刺激的个体化旨在使辅助生殖治疗达到最大的疗效和安全性，但就目前而言，在实现预后不良女性的理想成功率方面，它远非理想。这可能是由于未能识别出那些可能具有低预后的女性，而目前使用的预后特征无法识别这些女性。引入以患者为导向的策略，包括个体化卵母细胞数量（POSEIDON）概念，加强对这些低预后群体的识别，并根据重要的预后因素进行分层。POSEIDON 概念为这些女性的管理提供了一种实用方法，是咨询和临床管理的有用工具。在本评论中，我们重点关注 POSEIDON 组 2 标准的可能管理策略。
