[果糖胺与糖化血红蛋白用于评估糖尿病患者代谢控制情况的比较]

[Comparison of fructosamine and Hba1c for the evaluation of metabolic control of diabetic patients].

作者信息

Veillon H, Bovet P, Buchard P A, Darioli R

机构信息

Policlinique médicale universitaire, Lausanne.

出版信息

Schweiz Med Wochenschr. 1988 Dec 31;118(52):1989-92.

PMID:3217780

Abstract

Fructosamine values, and the influence thereon of age, BMI and sex, were determined in 384 nondiabetic individuals aged between 20 and 95 years. In this control group mean F levels were 2.45 +/- 0.25 mmol/l and were age-related only, rising from 2.3 in the second decade to 2.6 in the eighth. We compared F and HbA1c in 135 diabetic patients. F correlated with HbA1c in the diabetic group (r = 0.76, p less than 0.001). Because of its biological properties fructosamine could become a useful pointer in the metabolic follow-up of diabetic patients, especially where clinic visits are frequent.

摘要

在384名年龄在20至95岁之间的非糖尿病个体中测定了果糖胺值及其受年龄、体重指数和性别的影响。在这个对照组中，平均果糖胺水平为2.45±0.25 mmol/l，且仅与年龄相关，从第二个十年的2.3上升至第八个十年的2.6。我们比较了135名糖尿病患者的果糖胺和糖化血红蛋白。糖尿病组中果糖胺与糖化血红蛋白相关（r = 0.76，p<0.001）。由于其生物学特性，果糖胺可能成为糖尿病患者代谢随访中的一个有用指标，尤其是在频繁门诊就诊的情况下。