Department of Surgery, Weill Cornell Medical College, New York, New York.
Department of Healthcare Policy and Research, Weil Cornell Medical College, New York, New York.
Surg Obes Relat Dis. 2020 May;16(5):670-673. doi: 10.1016/j.soard.2020.02.007. Epub 2020 Feb 20.
With improved methods of identification and treatment, the numbers of cancer survivors are increasing. Weight loss is encouraged to reduce recurrence. After cancer treatment, will survivors respond to weight change and receive the benefits of bariatric surgery?
To compare weight loss after bariatric surgery of patients treated for cancer with those never diagnosed with cancer.
The 10 surgical centers participating in the Longitudinal Assessment of Bariatric Surgery (LABS2).
A retrospective review of the LABS database of 2458 participants was completed to determine which patients had answered the question that they had been told they had cancer with a positive response. Cancer survivors were compared for body mass index (calculated as weight in kilograms divided by height in meters squared) at baseline and 1, 3, 5, and 7 years after bariatric surgery with those who responded negatively to this question. Descriptive statistics, Fisher's exact tests, 2-sample independent t tests, Wilcoxon rank sum tests, and multiple linear regression were used.
Groups were significantly different in age (P < .0001) and surgery type (P = .02). Other demographic and clinical comparisons were nonsignificant at the .05 significance level. Cancer survivors demonstrated less weight loss at 1 year (P = .0001). Over 7 years, there was no significant difference between the 2 groups. Adjusting for age, sex, baseline body mass index, and surgery type, cancer history was not found to be significant predictor of body mass index change 1-year postbariatric surgery.
Patients treated for cancer are not different than the general population in their capacity for long-term weight loss with surgical assistance.
随着识别和治疗方法的改进，癌症幸存者的数量正在增加。减轻体重有助于减少复发。癌症治疗后，幸存者会对体重变化做出反应并从减肥手术中获益吗？
比较接受过癌症治疗的患者与从未被诊断出患有癌症的患者在减肥手术（减肥手术）后的体重减轻情况。
参与纵向评估减肥手术（LABS2）的 10 个手术中心。
对 LABS 数据库中的 2458 名参与者进行回顾性审查，以确定哪些患者对他们曾被告知患有癌症的问题回答为“是”。将癌症幸存者的体重指数（体重以千克为单位除以身高的平方得出）与对该问题回答“否”的患者进行比较，比较内容包括基线时、减肥手术后 1、3、5 和 7 年。使用描述性统计、Fisher 确切检验、2 样本独立 t 检验、Wilcoxon 秩和检验和多元线性回归。
两组在年龄（P <.0001）和手术类型（P =.02）上存在显著差异。在.05 显著性水平下，其他人口统计学和临床比较没有差异。癌症幸存者在 1 年内体重减轻较少（P =.0001）。7 年后，两组之间没有显著差异。调整年龄、性别、基线体重指数和手术类型后，癌症病史并不是减肥手术后 1 年体重指数变化的显著预测因素。
接受癌症治疗的患者在接受手术辅助的长期减肥能力方面与一般人群没有差异。
