School of Nursing, Fujian Medical University, Fuzhou, China.
Department of Hematology, Fujian Medical University Union Hospital, Fuzhou, China.
Support Care Cancer. 2020 Jun;28(6):2541-2552. doi: 10.1007/s00520-020-05383-3. Epub 2020 Mar 16.
To systematically review evidence regarding the benefits of Internet-based psycho-educational interventions among cancer patients.
We performed a systematic review with meta-analysis and qualitative evidence synthesis. Systematic searches for published studies in English or Chinese identified eligible randomized and clinical controlled trials. The following databases were searched: Medline, Embase, CINAHL, PsycINFO, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), Proquest Digital Dissertations, Foreign Medical Retrieval System, China National Knowledge Infrastructure, China Science and Technology Journal Database, China Wanfang Database, and Taiwanese Airiti Library. We also searched the gray literature and reviewed reference lists from relevant articles. Studies were scored for quality using the Cochrane Risk of Bias Tool.
Seven eligible studies (1220 participants) were identified that used three intervention tools: website programs (n = 5), e-mail counseling (n = 1), and a single-session psycho-educational intervention (n = 1). The quality of all studies was moderate. The meta-analysis showed that Internet-based psycho-educational interventions had a significant effect on decreasing depression (standardized mean difference (SMD) - 0.58, 95% confidence interval (CI) (- 1.12, - 0.03), p = 0.04) and fatigue (mean difference (MD) - 9.83, 95% CI (- 14.63, - 5.03), p < 0.01). However, there was no evidence for effects on distress (SMD - 1.03, 95% CI (- 2.63, 0.57), p = 0.21) or quality of life (MD 1.10, 95% CI (- 4.42, 6.63), p = 0.70).
Internet-based psycho-educational interventions reduce fatigue and depression in cancer patients. More rigorous studies with larger samples and long-term follow-up are warranted to investigate the effects of these interventions on cancer patient quality of life and other psychosocial outcomes.
系统回顾基于互联网的心理教育干预措施对癌症患者益处的证据。
我们进行了系统综述和荟萃分析以及定性证据综合。系统地检索了英文和中文发表的研究，以确定合格的随机和临床对照试验。检索了以下数据库：Medline、Embase、CINAHL、PsycINFO、Web of Science、Cochrane 对照试验中心注册库（CENTRAL）、Proquest 数字论文全文库、外文学术文献数据库、中国国家知识基础设施、中国科技期刊数据库、中国万方数据库和台湾学术文献数据库。我们还检索了灰色文献，并查阅了相关文章的参考文献列表。使用 Cochrane 偏倚风险工具对研究进行质量评分。
确定了 7 项合格研究（1220 名参与者），使用了三种干预工具：网站程序（n=5）、电子邮件咨询（n=1）和单次心理教育干预（n=1）。所有研究的质量均为中等。荟萃分析显示，基于互联网的心理教育干预措施可显著降低抑郁（标准化均数差（SMD）-0.58，95%置信区间（CI）（-1.12，-0.03），p=0.04）和疲劳（MD-9.83，95%CI（-14.63，-5.03），p<0.01）。然而，在痛苦（SMD-1.03，95%CI（-2.63，0.57），p=0.21）或生活质量（MD 1.10，95%CI（-4.42，6.63），p=0.70）方面没有证据表明存在效果。
基于互联网的心理教育干预措施可减轻癌症患者的疲劳和抑郁。需要进行更多严格的研究，纳入更大的样本并进行长期随访，以调查这些干预措施对癌症患者生活质量和其他心理社会结局的影响。
