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急性食管坏死(古尔维茨综合征):危重症患者糖尿病酮症酸中毒的一种罕见并发症。

Acute Esophageal Necrosis (Gurvits Syndrome): A Rare Complication of Diabetic Ketoacidosis in a Critically Ill Patient.

作者信息

Vien Linda P, Yeung Ho-Man

机构信息

Department of Medicine, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.

出版信息

Case Rep Med. 2020 Feb 27;2020:5795847. doi: 10.1155/2020/5795847. eCollection 2020.

DOI:10.1155/2020/5795847
PMID:32180810
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7063189/
Abstract

Acute esophageal necrosis (AEN) is a rare clinical diagnosis that primarily affects the distal third of the esophagus. AEN causes odynophagia, leading to decreased oral intake and food avoidance. AEN can arise in critically ill patients with multiple comorbidities and is an uncommon complication of diabetic ketoacidosis (DKA). We present a case of a young female with poorly controlled, insulin-dependent diabetes mellitus type 2 who developed odynophagia, small volume coffee-ground emesis, and inability to tolerate oral intake after resolution of DKA. She was found to have esophagitis with esophageal necrosis in the middle third of the esophagus on upper gastrointestinal endoscopy. She was subsequently treated with fluid resuscitation and gastric acid suppression and improved clinically with slow advancements in her diet. The location of her lesion in the more vascularized middle one-third of the esophagus and lack of significant blood pressure variations during her hospital stay make her case unique. Thus, AEN should be considered in the differential diagnosis for critically ill patients who present with vague symptoms such as odynophagia and gastrointestinal bleeding.

摘要

急性食管坏死(AEN)是一种罕见的临床诊断,主要影响食管远端三分之一。AEN导致吞咽痛,导致经口摄入量减少和回避食物。AEN可发生于患有多种合并症的危重症患者,是糖尿病酮症酸中毒(DKA)的一种罕见并发症。我们报告一例2型胰岛素依赖型糖尿病控制不佳的年轻女性病例,该患者在DKA缓解后出现吞咽痛、少量咖啡渣样呕吐物,且无法耐受经口摄入。上消化道内镜检查发现她食管中段有食管炎伴食管坏死。随后她接受了液体复苏和胃酸抑制治疗,并随着饮食缓慢推进而临床症状改善。她病变位于食管血管更丰富的中三分之一处,且住院期间血压无明显变化,这使得她的病例具有独特性。因此,对于出现吞咽痛和胃肠道出血等模糊症状的危重症患者,鉴别诊断时应考虑AEN。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd0c/7063189/bf3a1c483b9a/CRIM2020-5795847.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd0c/7063189/bf3a1c483b9a/CRIM2020-5795847.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd0c/7063189/bf3a1c483b9a/CRIM2020-5795847.001.jpg

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Cureus. 2023 Feb 14;15(2):e34989. doi: 10.7759/cureus.34989. eCollection 2023 Feb.
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