Zubair Mohammad
Department of Medical Microbiology, Faculty of Medicine, University of Tabuk, Tabuk 71491, Saudi Arabia.
World J Diabetes. 2020 Mar 15;11(3):78-89. doi: 10.4239/wjd.v11.i3.78.
Diabetic foot ulceration (DFU) is the prime health concern globally. It accounts for the major burden related to disease mortality and morbidity and economic cost. The timely and early recognition of the DFU can help present its occurrence and improve clinical outcomes.
To evaluate interrelationships between foot ulcers, risk factors, and antibiotic resistance among diabetic patients having ulcers in their foot.
The databases such as PubMed, ERIC, Medline, and Google Scholar were extensively used for the extraction of studies. The selected studies were published within the time-period of 2014-2018. Ten studies were selected, which were found to be completely relevant to the current study.
The prevalence of diabetic foot ulcers among the population was evaluated, and the associated risk factors with its prevalence. Moreover, few studies also reported on the bacteria that are found to be most prevailing among diabetic patients. A narrative discussion was drawn through this analysis, which was used to highlight the specific area of research through selected studies, extraction of the significant information that matched with the topic of research, and analysis of problem through the findings of the selected articles. The results helped in assessing significant knowledge regarding the risk factors of diabetic foot ulcers and the role of antimicrobial resistant in its treatment.
The gram-negative bacteria were found to be the most common reason for diabetic foot ulcers. The study only included 10 studies that are not sufficient to produce generalized results, and no information was reported on the tests required to analyze antimicrobial susceptibility that can guide clinicians to propose better and sound treatment plans. It is evident that most study results depicted that the most common risk factors were found to be hypertension and neuropathy.
糖尿病足溃疡（DFU）是全球主要的健康问题。它是疾病死亡率、发病率及经济成本相关的主要负担。及时且早期识别DFU有助于预防其发生并改善临床结局。
评估足部有溃疡的糖尿病患者中足部溃疡、危险因素及抗生素耐药性之间的相互关系。
广泛使用如PubMed、ERIC、Medline和谷歌学术等数据库来提取研究。所选研究发表于2014年至2018年期间。选取了10项研究，发现它们与当前研究完全相关。
评估了人群中糖尿病足溃疡的患病率及其相关危险因素。此外，少数研究还报告了在糖尿病患者中最常见的细菌。通过该分析进行了叙述性讨论，用于通过所选研究突出特定研究领域，提取与研究主题相符的重要信息，并通过所选文章的研究结果分析问题。这些结果有助于评估关于糖尿病足溃疡危险因素及抗菌药物耐药性在其治疗中的作用的重要知识。
革兰氏阴性菌被发现是糖尿病足溃疡最常见的原因。该研究仅纳入了10项研究，不足以得出普遍适用的结果，且未报告分析抗菌药物敏感性所需的检测信息，而这些信息可指导临床医生提出更好且合理的治疗方案。很明显，大多数研究结果表明最常见的危险因素是高血压和神经病变。
