Gomez Mariangela, Whiting Kerry, Naous Rana
Department of Pathology, SUNY Upstate Medical University, Syracuse, NY, USA.
SAGE Open Med Case Rep. 2020 Mar 4;8:2050313X20910598. doi: 10.1177/2050313X20910598. eCollection 2020.
Alveolar soft part sarcoma is a rare malignant soft tissue tumor, mainly localized in the extremities and occurring principally in adolescents and young adults. Alveolar soft part sarcoma are uncommon in the female genital tract. We here report a case of alveolar soft part sarcoma in a 20-year-old nullipara, presenting with vaginal bleeding and profound anemia requiring blood transfusions. Ultrasonographic examination revealed a polyp in the lower uterine segment. Surgical resection of the polyp was performed, and pathological evaluation showed typical histological, immunohistochemical, and molecular features consistent with alveolar soft part sarcoma. Patient underwent for total hysterectomy. Currently, she follows up with her surgeon and has no new complains. Given the infrequency of alveolar soft part sarcoma, this case report raises the awareness of alveolar soft part sarcoma as one of the entities to consider when confronted with a uterine polyp in a young patient.
肺泡软部肉瘤是一种罕见的恶性软组织肿瘤,主要位于四肢,主要发生于青少年和年轻成年人。肺泡软部肉瘤在女性生殖道中并不常见。我们在此报告一例20岁未生育女性的肺泡软部肉瘤病例,该患者表现为阴道出血和严重贫血,需要输血。超声检查发现子宫下段有一个息肉。对息肉进行了手术切除,病理评估显示典型的组织学、免疫组化和分子特征,与肺泡软部肉瘤一致。患者接受了全子宫切除术。目前,她在跟随外科医生进行随访,没有新的不适主诉。鉴于肺泡软部肉瘤的罕见性,本病例报告提高了对肺泡软部肉瘤的认识,使其成为年轻患者出现子宫息肉时需要考虑的疾病之一。