Soh Peter, Manning Bailey, Doan Ninh
Department of Neurology, University of South Alabama, Mobile, Alabama, USA.
Baptist Medical Center South, Montgomery, Alabama, USA.
Asian J Neurosurg. 2020 Feb 25;15(1):140-143. doi: 10.4103/ajns.AJNS_316_19. eCollection 2020 Jan-Mar.
Atypical central neurocytoma with extracranial metastases is a rare variant of benign central neurocytoma (CN). No definitive course of treatment exists for atypical CN. We report a unique case of atypical CN with concomitant pituitary macroadenoma and subsequent metastases to the spine. The patient received craniospinal radiation therapy. Close-follow up post tumor-resection may be advised to monitor for drop metastases. To the best of our knowledge, this is the only case reported of atypical CN with drop metastases to the spine concomitant with pathological-proven pituitary macroadenoma.
伴有颅外转移的非典型中枢神经细胞瘤是良性中枢神经细胞瘤（CN）的一种罕见变异类型。对于非典型CN，目前尚无明确的治疗方案。我们报告了一例独特的非典型CN病例，该病例同时伴有垂体大腺瘤，随后发生脊柱转移。患者接受了颅脊髓放射治疗。建议在肿瘤切除后密切随访，以监测是否出现播散性转移。据我们所知，这是唯一一例报告的伴有脊柱播散性转移且经病理证实伴有垂体大腺瘤的非典型CN病例。
