Worldwide Laser Institute, Dallas, TX, USA.
Department of Dermatology, Alpert Medical School of Brown University, Providence, RI, USA.
J Cosmet Dermatol. 2020 May;19(5):1057-1062. doi: 10.1111/jocd.13376. Epub 2020 Mar 17.
The periorbital region is among the first areas to be affected by the process of aging, which is influenced by genetic and constitutional factors. As the region plays an important role in overall facial appearance, rejuvenation of the area has immense cosmetic benefit and various treatment modalities have been used to achieve the same.
This article reviews commonly used non-surgical and minimally invasive modalities for periorbital rejuvenation.
The literature research considered published journal articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) and reference lists of respective articles. Only articles available in English were considered for this review.
Autologous platelet rich plasma (PRP) is increasingly used in dermatology for skin and hair conditions. The use of PRP is rapidly growing in popularity as a modality to achieve skin rejuvenation. The mechanism by which PRP leads to skin rejuvenation is by increasing the dermal fibroblast proliferation, expression of matrix metalloproteinase and collagen synthesis.
The evidence discussed in this article indicates the increasing importance of minimally invasive modalities in periorbital rejuvenation and a promising role for PRP as solo therapy or in multimodality regimens.
眼周区域是最早受衰老过程影响的区域之一，而衰老过程受到遗传和体质因素的影响。由于该区域对面部整体外观起着重要作用，因此该区域的年轻化具有巨大的美容益处，并且已经使用了各种治疗方式来达到这一效果。
本文综述了常用于眼周年轻化的非手术和微创治疗方式。
文献研究考虑了已发表的期刊文章（临床试验或科学综述）。通过搜索电子数据库（MEDLINE 和 PubMed）和各自文章的参考文献列表来确定研究。本综述仅考虑了英文可用的文章。
富含血小板的血浆（PRP）自体越来越多地用于皮肤科的皮肤和头发状况。PRP 作为一种实现皮肤年轻化的方式，其应用越来越受欢迎。PRP 导致皮肤年轻化的机制是通过增加真皮成纤维细胞的增殖、基质金属蛋白酶的表达和胶原蛋白的合成。
本文讨论的证据表明，微创治疗方式在眼周年轻化中的重要性日益增加，PRP 作为单一疗法或多模式治疗方案具有广阔的应用前景。
