From the Division of Plastic Surgery, Baylor College of Medicine; and the Dallas Plastic Surgery Institute.
Plast Reconstr Surg. 2021 Jan 1;147(1):219-230. doi: 10.1097/PRS.0000000000007509.
The use of platelet-rich plasma has emerged as one of the most desired nonsurgical treatments for facial rejuvenation and hair restoration. It has grown to encompass a wide variety of applications within the field of plastic surgery, including its use in combination with microneedling, laser, and fat-grafting procedures.
In this article, the authors aim to (1) describe the preparation process of platelet-rich plasma; (2) discuss the proposed science behind platelet-rich plasma with regard to its evolving role in hair restoration and facial rejuvenation; and (3) highlight the recent literature examining its widespread use.
Based on the available literature, there is a therapeutic advantage to the use of platelet-rich plasma as a single treatment modality for alopecia and skin rejuvenation and in combination with laser skin treatment and fat grafting. There is, however, a considerable amount of variability in the processing, preparation, and treatment modalities.
Despite a lack of standardized protocols for platelet-rich plasma preparation and a scarcity of large-scale studies with long-term follow-up, there is convincing evidence with objective measurement modalities that display positive outcomes after treatment for skin rejuvenation, hair regrowth, wound healing, and fat graft take.
富血小板血浆的应用已成为最受期待的非手术面部年轻化和毛发修复治疗方法之一。它在整形手术领域的应用不断扩展，包括与微针、激光和脂肪移植手术联合应用。
本文作者旨在：（1）描述富血小板血浆的制备过程；（2）讨论富血小板血浆在毛发修复和面部年轻化方面的作用不断发展的科学依据；（3）强调最近有关其广泛应用的文献。
根据现有文献，富血小板血浆作为单一治疗方法治疗脱发和皮肤年轻化，以及与激光皮肤治疗和脂肪移植联合应用，具有治疗优势。然而，在处理、制备和治疗方式方面存在相当大的差异。
尽管富血小板血浆制备缺乏标准化方案，且缺乏长期随访的大规模研究，但仍有令人信服的证据，客观测量方法显示，在皮肤年轻化、毛发生长、伤口愈合和脂肪移植成活率方面，治疗后有积极的效果。
