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复发性角膜糜烂综合征的角膜敏感性和泪液功能。

Corneal Sensitivity and Tear Function in Recurrent Corneal Erosion Syndrome.

机构信息

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出版信息

Invest Ophthalmol Vis Sci. 2020 Mar 9;61(3):21. doi: 10.1167/iovs.61.3.21.

Abstract

PURPOSE

To determine the association of corneal sensitivity and tear functions on the prognosis of eyes after posttraumatic recurrent corneal erosion syndrome (RCES).

METHODS

Patients were enrolled retrospectively and had unilateral RCES and a history of ocular surface trauma. A corneal sensitivity test and tear function test (tear break-up time and Schirmer test) were performed at three time points (month 1 to month 3, month 3 to month 6, and month 6 to month 12). Depending on the number of recurrences during the follow-up, patients were divided into group A (n > 2) or group B (n = 2). A comparison between diseased and normal fellow eyes in each patient was performed.

RESULTS

A total of 31 patients were enrolled and divided into group A (n = 14) and group B (n = 17). The mean age was 40.3 ± 12.2 years, whereas the mean follow-up was 28.0 ± 3.6 months. During the study period, corneal sensitivity, tear break-up time, and the Schirmer test results were all lower in diseased eyes than in normal fellow eyes in both groups. Compared to the first time point, recovery of corneal sensitivity and the Schirmer test values were observed in diseased eyes in group B at the second and third time points.

CONCLUSIONS

Poor corneal sensitivity and tear function are associated with posttraumatic RCES. Recovery of corneal sensitivity and tear function may be associated with a reduction of recurrence in eyes with posttraumatic RCES.

摘要

目的

探讨角膜敏感性和泪液功能与创伤后复发性角膜上皮糜烂综合征(RCES)预后的关系。

方法

回顾性纳入单侧 RCES 且有眼表外伤史的患者。在三个时间点(第 1 至 3 个月、第 3 至 6 个月和第 6 至 12 个月)进行角膜敏感性测试和泪液功能测试(泪膜破裂时间和 Schirmer 试验)。根据随访期间的复发次数,患者分为 A 组(n > 2)或 B 组(n = 2)。对每位患者的病眼和正常对侧眼进行比较。

结果

共纳入 31 例患者,分为 A 组(n = 14)和 B 组(n = 17)。平均年龄为 40.3 ± 12.2 岁,平均随访时间为 28.0 ± 3.6 个月。研究期间,两组患者病眼的角膜敏感性、泪膜破裂时间和 Schirmer 试验结果均低于正常对侧眼。与第一次时间点相比,B 组病眼的角膜敏感性和 Schirmer 试验值在第二次和第三次时间点恢复。

结论

较差的角膜敏感性和泪液功能与创伤后 RCES 相关。病眼角膜敏感性和泪液功能的恢复可能与创伤后 RCES 眼复发减少有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eea0/7401482/7b470f53b000/iovs-61-3-21-f001.jpg

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