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营养支持团队:系统评价。

Nutrition Support Teams: A Systematic Review.

机构信息

KCE Belgian Health Care Knowledge Centre, Brussels, Belgium.

出版信息

JPEN J Parenter Enteral Nutr. 2020 Aug;44(6):1004-1020. doi: 10.1002/jpen.1811. Epub 2020 Mar 17.

Abstract

BACKGROUND

The concept of a nutrition support team (NST) was first introduced at the end of the 20th century in the US and Europe. Expected benefits include reduced (inappropriate) prescription of (par)enteral nutrition; however, to the authors' knowledge, no recent review has assessed the effectiveness of NSTs. Therefore, this systematic review evaluated the effectiveness of NSTs with respect to the prevalence of adult patients receiving (par)enteral nutrition.

METHODS

Five literature databases were searched and completed by citing searches. Studies on NSTs that were published between 2000 and 2018 in Western countries, applied a comparative design, and contained at least outcome data on the prevalence of (par)enteral nutrition were included. Analyses were mainly descriptive because of high heterogeneity that prevented meta-analyses.

RESULTS

The 27 included studies mainly originated from the UK and US. Only 1 of the included studies was a randomized trial; the other studies had a pre-post design (n = 17) or compared groups in a nonrandomized way. All but 2 studies were performed in acute care hospitals, and 5 studies focused only on intensive care patients. There was conflicting evidence of whether NSTs lead to reduction or increase in patients starting parenteral nutrition (PN); however, weak evidence suggested that NSTs might lead to an increase in the ratio of enteral nutrition to PN use and might decrease inappropriate PN use.

CONCLUSION

Although almost all studies concluded in favor of NSTs, the evidence base is weak and insufficient because of a lack of well-designed studies and successful outcomes.

摘要

背景

营养支持团队(NST)的概念于 20 世纪末首先在美国和欧洲提出。预期的益处包括减少(不适当的)肠外营养处方;然而,据作者所知,最近没有任何审查评估过 NST 的效果。因此,本系统评价评估了 NST 在接受肠外营养的成年患者患病率方面的效果。

方法

检索了 5 个文献数据库,并通过引用搜索进行了补充。纳入了 2000 年至 2018 年在西方国家发表的、采用比较设计且至少包含关于肠外营养患病率的结局数据的 NST 研究。由于高度异质性,妨碍了荟萃分析,因此主要进行描述性分析。

结果

27 项纳入的研究主要来自英国和美国。纳入的研究中仅有 1 项为随机试验;其余研究采用了前后设计(n=17)或非随机比较组设计。除了 2 项研究外,所有研究均在急性护理医院进行,5 项研究仅关注重症监护患者。NST 是否导致开始肠外营养(PN)的患者减少或增加存在相互矛盾的证据;然而,证据较弱表明 NST 可能导致肠内营养与 PN 使用率的比值增加,并可能减少不适当的 PN 使用。

结论

尽管几乎所有研究都支持 NST,但由于缺乏精心设计的研究和成功的结果,证据基础仍然薄弱且不足。

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