Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Key Laboratory of Organ Transplantation, Ministry of Education, Ministry of Public Health, Chinese Academy of Medical Sciences, Wuhan, China.
Am J Transplant. 2020 Jul;20(7):1859-1863. doi: 10.1111/ajt.15869. Epub 2020 Mar 31.
The current outbreak of Coronavirus Disease 2019 (COVID-19) has raised great concern worldwide, but its impact on transplant recipients is unknown. We report here the clinical features and therapeutic course of the first reported renal transplant recipient with confirmed COVID-19 pneumonia. This is a 52-year-old man who received kidney transplantation 12 years ago. His overall clinical characteristics (symptoms, laboratory examinations, and chest CT) were similar to those of non-transplanted COVID-19 patients. Following a treatment regimen consisting of reduced immunosuppressant use and low dose methylprednisolone-based therapy, the COVID-19 pneumonia in this long-term immunosuppressive patient was successfully recovered. This effectively treated case has reference value for the future treatment of other transplant patients with COVID-19 pneumonia.
目前 2019 年冠状病毒病（COVID-19）的爆发引起了全世界的极大关注，但它对移植受者的影响尚不清楚。我们在此报告首例经确认的 COVID-19 肺炎肾移植受者的临床特征和治疗经过。这是一位 52 岁男性，12 年前接受了肾移植。他的整体临床特征（症状、实验室检查和胸部 CT）与非移植 COVID-19 患者相似。在接受减少免疫抑制剂使用和低剂量甲基强的松龙为基础的治疗方案后，这位长期免疫抑制患者的 COVID-19 肺炎成功康复。这一有效治疗的病例对未来治疗其他 COVID-19 肺炎的移植患者具有参考价值。
