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肝移植受者严重 COVID-19 肺炎的成功治疗。

Successful treatment of severe COVID-19 pneumonia in a liver transplant recipient.

机构信息

Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan, China.

出版信息

Am J Transplant. 2020 Jul;20(7):1891-1895. doi: 10.1111/ajt.15901. Epub 2020 Apr 19.

DOI:10.1111/ajt.15901
PMID:32243673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9800465/
Abstract

Coronavirus disease 2019 (COVID-19) pandemic spreads rapidly and may be an increasing challenge for transplant community. Clinical data on COVID-19 infection in transplant population is very limited. Herein we presented the clinical course and outcome of a 50-year-old male post liver transplantation who contracted COVID-19, with subsequent infection of his wife. The process of illness was representative. A therapeutic regime with temporary immunosuppression withdrawal and systemic low-dose corticosteroid as principle was involved in the management of the patient which made him recover from severe COVID-19 pneumonia.

摘要

2019 年冠状病毒病(COVID-19)疫情迅速蔓延,可能对移植界构成越来越大的挑战。关于移植人群中 COVID-19 感染的临床数据非常有限。在此,我们介绍了一名 50 岁男性肝移植后感染 COVID-19 及其妻子随后感染的临床过程和转归。该患者的发病过程具有代表性。治疗方案涉及暂时停用免疫抑制剂和全身小剂量皮质类固醇,使他从重症 COVID-19 肺炎中康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b88/9800465/469225f7e027/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b88/9800465/7a608cf710b3/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b88/9800465/469225f7e027/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b88/9800465/7a608cf710b3/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b88/9800465/469225f7e027/gr2_lrg.jpg

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Protocol for Prevention and Control of COVID-19 (Edition 6).新型冠状病毒肺炎防控方案(第六版)
China CDC Wkly. 2020 May 8;2(19):321-326. doi: 10.46234/ccdcw2020.082.
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Coronaviruses and Immunosuppressed Patients: The Facts During the Third Epidemic.冠状病毒与免疫抑制患者:第三次疫情期间的实际情况
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COVID-19 infection in a child following liver transplantation.肝移植术后儿童感染新型冠状病毒肺炎
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Evaluation of the therapeutic regimen in COVID-19 in transplant patients: where do immunomodulatory and antivirals stand?评估 COVID-19 移植患者的治疗方案:免疫调节剂和抗病毒药物的地位如何?
Virol J. 2021 Nov 22;18(1):228. doi: 10.1186/s12985-021-01700-2.
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World J Hepatol. 2021 Oct 27;13(10):1299-1315. doi: 10.4254/wjh.v13.i10.1299.
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