Harefield Respiratory Research Group and.
National Heart and Lung Institute and.
Am J Respir Crit Care Med. 2020 Jun 15;201(12):1517-1524. doi: 10.1164/rccm.201909-1878OC.
Pulmonary rehabilitation (PR) after hospitalizations for exacerbations of chronic obstructive pulmonary disease (COPD) improves exercise capacity and health-related quality of life and reduces readmissions. However, posthospitalization PR uptake is low. To date, no trials of interventions to increase uptake have been conducted. To study the effect of a codesigned education video as an adjunct to usual care on posthospitalization PR uptake. The present study was an assessor- and statistician-blinded randomized controlled trial with nested, qualitative interviews of participants in the intervention group. Participants hospitalized with COPD exacerbations were assigned 1:1 to receive either usual care (COPD discharge bundle including PR information leaflet) or usual care plus the codesigned education video delivered via a handheld tablet device at discharge. Randomization used minimization to balance age, sex, FEV % predicted, frailty, transport availability, and previous PR experience. The primary outcome was PR uptake within 28 days of hospital discharge. A total of 200 patients were recruited, and 196 were randomized (51% female, median FEV predicted, 36 [interquartile range, 27-48]). PR uptake was 41% and 34% in the usual care and intervention groups, respectively ( = 0.37), with no differences in secondary (PR referral and completion) or safety (readmissions and death) endpoints. A total of 6 of the 15 participants interviewed could not recall receiving the video. A codesigned education video delivered at hospital discharge did not improve posthospitalization PR uptake, referral, or completion.
慢性阻塞性肺疾病(COPD)急性加重住院后进行肺康复(PR)可提高运动能力和健康相关生活质量,并降低再入院率。然而,住院后接受 PR 的比例较低。迄今为止,尚未开展任何旨在提高接受程度的干预措施的试验。本研究旨在评估一种辅助常规护理的代码设计教育视频对住院后 PR 接受度的影响。这是一项评估者和统计师设盲的随机对照试验,对干预组参与者进行了嵌套的定性访谈。因 COPD 加重而住院的患者按 1:1 随机分配,分别接受常规护理(包括 PR 信息传单的 COPD 出院套餐)或常规护理加出院时通过手持平板电脑提供的代码设计教育视频。随机化使用最小化方法来平衡年龄、性别、FEV %预测值、虚弱程度、交通可用性和以前的 PR 经验。主要结局是在出院后 28 天内接受 PR。共招募了 200 名患者,其中 196 名患者被随机分配(51%为女性,中位 FEV 预测值为 36 [四分位间距 27-48])。常规护理组和干预组的 PR 接受率分别为 41%和 34%( = 0.37),次要结局(PR 转诊和完成)和安全性结局(再入院和死亡)均无差异。接受访谈的 15 名参与者中有 6 名无法回忆起收到视频。在出院时提供的代码设计教育视频并未提高住院后 PR 的接受度、转诊率或完成率。