Senff H, Bothe C, Riemann U, Reinel D
Abteilung für Dermatologie und Venerologie, Bundeswehrkrankenhauses Hamburg.
Z Hautkr. 1988 Dec 15;63(12):1005-8.
In a clinical study from October 1985 to July 1987, we tested the efficacy of 3 different imidazole compounds in 112 male patients suffering from pityriasis versicolor. The diagnosis was made according to clinical criteria and confirmed by microscopical investigation. Our results prove the necessity of daily treatment over a period of at least 2 weeks. After 2 weeks, the microscopical examination should be repeated. Sprays and shampoos seemed equally effective. The relapse rate turned out to be rather high. The symptom-free interval between therapy and relapse could not be correlated to any of the forms of treatment. Those patients who had to be treated for more than 2 weeks were most likely to develop a relapse within a shorter period.
在1985年10月至1987年7月的一项临床研究中，我们对112名患有花斑癣的男性患者测试了3种不同咪唑化合物的疗效。诊断依据临床标准做出，并通过显微镜检查得以证实。我们的结果证明了至少持续2周每日治疗的必要性。2周后，应重复进行显微镜检查。喷雾和洗发水似乎同样有效。复发率相当高。治疗与复发之间的无症状间隔与任何一种治疗方式均无关联。那些必须接受治疗超过2周的患者最有可能在更短时间内复发。
