比较四种根管生物材料和氢氧化钙对模拟未成熟牙抗折性能影响的评价。

Comparative evaluation of four endodontic biomaterials and calcium hydroxide regarding their effect on fracture resistance of simulated immature teeth.

机构信息

Assistant professor, Department of Paediatric Dentistry, Faculty of Dentistry, Kahramanmara? Sütçü ?mam Üniversity, Kahramanmara?, Turkey.

Associate professor, Department of Paediatric Dentistry, Faculty of Dentistry, Kirikkale University, Kirikkale, Turkey.

出版信息

Eur J Paediatr Dent. 2020 Mar;21(1):23-28. doi: 10.23804/ejpd.2020.21.01.05.

DOI:10.23804/ejpd.2020.21.01.05

PMID:32183524

Abstract

AIM

Single-session apexification treatment with MTA is an alternative to the root-canal treatment of immature teeth. Since its results are far from ideal, research with MTA-derivative biomaterials continues; however, the number of studies is limited as of yet. This study aimed to compare the fragilities of in vitro-simulated immature teeth in single-session apexification with MTA and newly-developed calcium-silicate-based MTA derivatives.

MATERIALS AND METHODS

Two hundred seventy human permanent upper incisors were randomly divided into study (n = 180), positive control (Ca (OH)2) (n = 45), and negative control (NC-intact) (n = 45) groups. The study groups used ProRoot MTA (MTA-PR), MM-MTA, NeoMTA-Plus, and Biodentine (BD). Two-week, two-month, and one-year follow-ups data were recorded. A fracture resistance (FR) test was performed at the end of each period. The results of the biomaterials at the different follow-up timepoints were statistically analysed and compared.

RESULTS

The two-week FR medians were significantly lower in MM-MTA, NEO, MTA-PR, and Ca (OH)2 groups (p<0.001, p<0.001, p=0.003, and p<0.001. respectively), compared to NC. The two-month FR medians were significantly lower in BD, MM-MTA, NEO, MTA-PR, and Ca (OH)2, (p=0.005, p<0.001, p<0.001, p<0.001, and p<0.001, respectively) compared to NC. The one-year FR medians were significantly lower in the BD, MM-MTA, NEO, MTA-PR, and Ca (OH)2 groups (p=0.002, p<0.001, p<0.001, p<0.001, and p<0.001, respectively) compared to NC. For all groups, FR at the one-year mark was significantly lower compared to the two-week and two-month marks (p<0.001, p<0.001).

STATISTICS

All groups were compared with each other regarding fracture resistance at two weeks, two months, and one year. Also, for each group follow-up data on fracture resistance were compared.

CONCLUSIONS

Since FR was significantly higher at the two-week and the two-month mark compared to the one-year mark for each material, filling the root canal completely with biomaterials used in our study leads to tooth denaturation over time, with effects like Ca (OH)2.

摘要

目的

MTA 一次性根尖诱导成形术是未成熟恒牙根管治疗的替代方法。由于其效果远不理想，因此仍在继续研究 MTA 衍生的生物材料；然而，到目前为止，研究数量仍然有限。本研究旨在比较 MTA 和新型钙硅酸钠基 MTA 衍生物在一次性根尖诱导成形术中对体外模拟未成熟恒牙的脆弱性。

材料和方法

将 270 颗人上颌恒中切牙随机分为研究组（n = 180）、阳性对照组（Ca（OH）2）（n = 45）和阴性对照组（NC-完整）（n = 45）。研究组使用 ProRoot MTA（MTA-PR）、MM-MTA、NeoMTA-Plus 和 Biodentine（BD）。在每个时期结束时进行抗折强度（FR）测试。对不同随访时间点的生物材料结果进行统计学分析和比较。

结果

与 NC 相比，MM-MTA、NEO、MTA-PR 和 Ca（OH）2 组的两周 FR 中位数显著降低（p<0.001、p<0.001、p=0.003 和 p<0.001）。与 NC 相比，BD、MM-MTA、NEO、MTA-PR 和 Ca（OH）2 组的两个月 FR 中位数显著降低（p=0.005、p<0.001、p<0.001、p<0.001 和 p<0.001）。与 NC 相比，BD、MM-MTA、NEO、MTA-PR 和 Ca（OH）2 组的一年 FR 中位数显著降低（p=0.002、p<0.001、p<0.001、p<0.001 和 p<0.001）。与两周和两个月相比，所有组的一年 FR 均显著降低（p<0.001、p<0.001）。