家庭因素在乌干达南部感染 HIV 的青少年接受抗逆转录病毒治疗（ART）自我效能中的作用。
The role of family factors in antiretroviral therapy (ART) adherence self-efficacy among HIV-infected adolescents in southern Uganda.
机构信息
Washington University in St. Louis, Brown School of Social Work, One Brookings Drive, St. Louis, MO, 63130, USA.
Washington University in St. Louis, St. Louis, MO, USA.
出版信息
BMC Public Health. 2020 Mar 17;20(1):340. doi: 10.1186/s12889-020-8361-1.
BACKGROUND
Adolescents living with HIV in sub-Saharan Africa are a vulnerable group at the intersection of poverty and health disparities. The family is a vital microsystem that provides financial and emotional support to achieve optimal antiretroviral therapy (ART) adherence. In this study, we explore the association between family factors and ART adherence self-efficacy, a significant psychological concept playing a critical role in ART adherence.
METHODS
Data from an NIH-funded study called Suubi + Adherence, an economic empowerment intervention for HIV positive adolescents (average age = 12.4 years) in southern Uganda was analyzed. We conducted multilevel regression analyses to explore the protective family factors, measured by family cohesion, child-caregiver communication and perceived child-caregiver support, associated with ART adherence self-efficacy.
RESULTS
The average age was 12.4 years and 56.4% of participants were female. The average household size was 5.7 people, with 2.3 children> 18 years. Controlling for sociodemographic and household characteristics, family cohesion (β = 0.397, p = 0.000) and child-caregiver communication (β = 0.118, p = 0.026) were significantly associated with adherence self-efficacy to ART.
CONCLUSION
Findings point to the need to strengthen family cohesion and communication within families if we are to enhance adherence self-efficacy among adolescents living with HIV.
TRIAL REGISTRATION
This trial was registered with ClinicalTrials.gov (registration number: NCT01790373) on 13 February 2013.
背景
撒哈拉以南非洲的艾滋病毒感染者青少年是处于贫困和健康差异交叉点的脆弱群体。家庭是一个重要的微观系统，为实现最佳抗逆转录病毒治疗（ART）依从性提供经济和情感支持。在这项研究中，我们探讨了家庭因素与 ART 依从性自我效能之间的关联，ART 依从性自我效能是一个重要的心理概念，在 ART 依从性中起着关键作用。
方法
对美国国立卫生研究院（NIH）资助的一项名为 Suubi+Adherence 的研究的数据进行了分析，该研究是乌干达南部艾滋病毒阳性青少年（平均年龄为 12.4 岁）的一项经济赋权干预措施。我们进行了多层次回归分析，以探讨保护性家庭因素与 ART 依从性自我效能的关系，这些保护性家庭因素通过家庭凝聚力、儿童-照顾者沟通和感知到的儿童-照顾者支持来衡量。
结果
参与者的平均年龄为 12.4 岁，其中 56.4%为女性。平均家庭规模为 5.7 人，有 2.3 个>18 岁的孩子。在控制了社会人口学和家庭特征后，家庭凝聚力（β=0.397，p=0.000）和儿童-照顾者沟通（β=0.118，p=0.026）与 ART 依从性自我效能显著相关。
结论
研究结果表明，如果我们要增强艾滋病毒感染者青少年的依从性自我效能，就需要加强家庭内的凝聚力和沟通。
试验注册
该试验于 2013 年 2 月 13 日在 ClinicalTrials.gov 注册（注册号：NCT01790373）。
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