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孔源性视网膜脱离玻璃体切除术后硅油乳化

Silicone Oil Emulsification after Vitrectomy for Rhegmatogenous Retinal Detachment.

作者信息

Yu Jian, Zong Yuan, Jiang Chunhui, Zhu Haohao, Deng Guohua, Xu Gezhi

机构信息

Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai 200031, China.

Key Laboratory of Myopia of State Health Ministry, Key Laboratory of Visual Impairment and Restoration of Shanghai, Shanghai 200031, China.

出版信息

J Ophthalmol. 2020 Feb 24;2020:6940625. doi: 10.1155/2020/6940625. eCollection 2020.

Abstract

PURPOSE

To investigate the characteristics of silicone oil (SO) emulsification after vitrectomy for rhegmatogenous retinal detachment and their possible correlations with clinical factors.

METHODS

The first 2 mL of washing out fluid after SO removal was collected, and used for the measurement of the size and number of SO droplets using a Multisizer® 3 Coulter counter (Beckman Coulter, USA). The correlations between SO droplets and clinical factors were analyzed.

RESULTS

A total of 38 patients (23 males, 15 females) who underwent primary PPV with SO injection for RRD and whose retina stayed attached for ≥3 months after SO removal were included in the study. The average number of oil droplets was 1.96 × 10 ± 3.95 × 10/mL (range 0.17 × 10 to 21.71 × 10/ml), and 80.8% (range 64.23%-99.07%) of the droplets were 1-2 m in diameter. The total number of emulsified SO droplets was not correlated with any clinical factor (all > 0.05). When the emulsified SO droplets were divided into groups by their diameter, multiple linear regression revealed that age was negatively correlated with the numbers of 5-7-m in diameter. The total number of emulsified SO droplets was not correlated with any clinical factor (all m in diameter. The total number of emulsified SO droplets was not correlated with any clinical factor (all > 0.05). When the emulsified SO droplets were divided into groups by their diameter, multiple linear regression revealed that age was negatively correlated with the numbers of 5-7-m in diameter. The total number of emulsified SO droplets was not correlated with any clinical factor (all m in diameter. The total number of emulsified SO droplets was not correlated with any clinical factor (all > 0.05). When the emulsified SO droplets were divided into groups by their diameter, multiple linear regression revealed that age was negatively correlated with the numbers of 5-7.

CONCLUSION

Using a Multisizer® Coulter counter, we successfully determined the number and size of SO droplets after emulsification. We found that the number of 5-12-m-diameter droplets was higher in younger-age patients and was higher in patients using antiglaucoma eyedrops.m in diameter. The total number of emulsified SO droplets was not correlated with any clinical factor (all.

摘要

目的

探讨孔源性视网膜脱离玻璃体切除术后硅油(SO)乳化的特征及其与临床因素的可能相关性。

方法

收集硅油取出后最初的2 mL冲洗液,使用Multisizer® 3库尔特计数器(美国贝克曼库尔特公司)测量硅油微滴的大小和数量。分析硅油微滴与临床因素之间的相关性。

结果

本研究纳入了38例患者(男性23例,女性15例),这些患者因孔源性视网膜脱离接受了初次玻璃体切除联合硅油注射,且在硅油取出后视网膜附着≥3个月。硅油微滴的平均数量为1.96×10±3.95×10/mL(范围为0.17×10至21.71×10/ml),80.8%(范围为64.23%-99.07%)的微滴直径为1-2μm。乳化硅油微滴的总数与任何临床因素均无相关性(均P>0.05)。当按直径将乳化硅油微滴分组时,多元线性回归显示年龄与直径为5-7μm的微滴数量呈负相关。乳化硅油微滴的总数与任何临床因素均无相关性(均P>0.05)。当按直径将乳化硅油微滴分组时,多元线性回归显示年龄与直径为5-7μm的微滴数量呈负相关。乳化硅油微滴的总数与任何临床因素均无相关性(均P>0.05)。当按直径将乳化硅油微滴分组时,多元线性回归显示年龄与直径为5-7μm的微滴数量呈负相关。

结论

使用Multisizer®库尔特计数器,我们成功测定了乳化后硅油微滴的数量和大小。我们发现,年龄较小的患者中直径为5-12μm的微滴数量较多,且使用抗青光眼眼药水的患者中该微滴数量也较多。乳化硅油微滴的总数与任何临床因素均无相关性(均P>0.05)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9011/7060885/58fe093aeafb/JOPH2020-6940625.001.jpg

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