Thoracic Surgery, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000 Zhejiang, China.
School of Food (Biology) Engineering, Xuzhou University of Technology, Xuzhou, 221018 Jiangsu, China.
Biomed Res Int. 2020 Feb 22;2020:7530498. doi: 10.1155/2020/7530498. eCollection 2020.
To investigate the pulmonary function responses to respiratory muscle training (RMT) in individuals with tetraplegia and provide a systematic review of the included studies.
Computerized retrieval of randomized controlled trials (RCT) in PubMed, Embase, and the Cochrane Library on the improvement of respiratory function in patients with spinal cord injury by RMT was conducted until May 2019. Two researchers independently screened the literature, extracted the data, and evaluated the risk of bias in the included studies. Articles were scored for their methodological quality using the Cochrane Collaboration risk of bias assessment tool.
Sixteen studies were identified. A significant benefit of RMT was revealed for five outcomes: force vital capacity (FVC, WMD: -0.43, 95% CI -0.84 to -0.03, = 0.037), vital capacity (VC, WMD: -0.40, 95% CI -0.69 to -0.12, = 0.037), vital capacity (VC, WMD: -0.40, 95% CI -0.69 to -0.12, = 0.037), vital capacity (VC, WMD: -0.40, 95% CI -0.69 to -0.12, = 0.037), vital capacity (VC, WMD: -0.40, 95% CI -0.69 to -0.12, = 0.037), vital capacity (VC, WMD: -0.40, 95% CI -0.69 to -0.12.
Our findings demonstrate that RMT can effectively improve spinal cord injury pulmonary function of the patient, which is marked by increasing respiratory strength, function, and endurance. Limited by the quantity and quality of the included studies, the above conclusion needs to be verified by more high-quality studies.
探讨呼吸肌训练（RMT）对四肢瘫痪患者肺功能的影响，并对纳入研究进行系统评价。
计算机检索 PubMed、Embase 和 Cochrane Library 中关于 RMT 改善脊髓损伤患者呼吸功能的随机对照试验（RCT），检索时限截至 2019 年 5 月。由 2 名研究者独立筛选文献、提取资料和评价纳入研究的偏倚风险，采用 Cochrane 协作网偏倚风险评估工具对纳入文献进行方法学质量评分。
共纳入 16 项研究。RMT 可显著改善 5 项指标：用力肺活量（FVC，WMD：-0.43，95%CI-0.84 至-0.03， = 0.037）、肺活量（VC，WMD：-0.40，95%CI-0.69 至-0.12， = 0.037）、最大吸气量（IC，WMD：-0.40，95%CI-0.69 至-0.12， = 0.037）、第一秒用力呼气量（FEV1，WMD：-0.40，95%CI-0.69 至-0.12， = 0.037）和最大通气量（MVV，WMD：-0.40，95%CI-0.69 至-0.12）。
RMT 能有效改善脊髓损伤患者的肺功能，表现为呼吸力量、功能和耐力的提高。受纳入研究数量和质量的限制，上述结论尚需更多高质量研究予以验证。
